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| Product Name | Pemetrexed Disodium Heptahydrate |
| Description |
Folate-dependent enzyme inhibitor |
| Purity | >98% (TLC, HPLC); NMR (Conforms) |
| CAS No. | 357166-29-1 |
| Molecular Formula | C20H19N5Na2O6 [7H2O] |
| Molecular Weight | 597.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in Water (100 mg/ml) |
| Source | Synthetic |
| SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.O.[Na+].[Na+] |
| InChI | InChI=1S/C20H21N5O6.2Na.7H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;;;;;;;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,2 |
| InChIKey | QJVSMHJWAOSBMD-MYXYZBIASA-L |
| Safety Phrases |
Hazard Statement(s): H315 : Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation Precautionary Statement Codes: P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
| Cite This Product | Pemetrexed Disodium Heptahydrate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-583) |
Biological Description
| Alternative Names | N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt; LY231514 |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 135564751 |
| Scientific Background | Folate antimetabolite inhibiting nucleotide biosynthesis enzymes. Used in cancer, with implications for studying DNA damage and apoptosis in neural cells. |
| References | 1. McLeod H.L., et al. (2000) Clin Can Research: Clin Trials. 6(7): 2677-2684. |
Product Images
![<p>Chemical structure of Pemetrexed Disodium Heptahydrate (SIH-583), a folate-dependent enzyme inhibitor. CAS #: 357166-29-1. Molecular Formula: C20H19N5Na2O6 [7H2O]. Molecular Weight: 597.5 g/mol.</p>](https://www.stressmarq.com/wp-content/uploads/SIH-583-Pemetrexed-Disodium-Heptahydrate-Chemical-Structure.png)
Chemical structure of Pemetrexed Disodium Heptahydrate (SIH-583), a folate-dependent enzyme inhibitor. CAS #: 357166-29-1. Molecular Formula: C20H19N5Na2O6 [7H2O]. Molecular Weight: 597.5 g/mol.
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