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| Product Name | Rucaparib phosphate |
| Description |
PARP Inhibitor |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 459868-92-9 |
| Molecular Formula | C19H18FN3O * H3PO4 |
| Molecular Weight | 421.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (25 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow powder |
| SMILES | O=C1NCCC2=C(C3=CC=C(CNC)C=C3)NC4=CC(F)=CC1=C24.OP(O)(O)=O |
| InChI | InChI=1S/C19H18FN3O.H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-5(2,3)4/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24);(H3,1,2,3,4) |
| InChIKey | FCCGJTKEKXUBFZ-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Rucaparib phosphate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-580) |
Biological Description
| Alternative Names | 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one, phosphate; AG-14699; PF01367338 |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, PARP Inhibitors |
| PubChem ID | 9931953 |
| Scientific Background | PARP1/2/3 inhibitor used in oncology. Studied in neurodegeneration for DNA damage response and neuronal survival. |
| References |
1. https://pubchem.ncbi.nlm.nih.gov/compound/rucaparib 2. Dockery L.E., Gunderson C.C., and Moore K.N. (2017) Onco Target Ther. 10: 3029-3037. 3. Syed Y.Y. (2017) Drugs. 77(5): 585-592. |
Product Images
Chemical structure of Rucaparib phosphate (SIH-580), a PARP Inhibitor. CAS #: 459868-92-9. Molecular Formula: C19H18FN3O * H3PO4. Molecular Weight: 421.4 g/mol.
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