Discovery through Partnership | Excellence through Quality
| Product Name | TEMPO |
| Description |
Stable Nitroxyl Radical |
| Purity | >98% |
| CAS No. | 2564-83-2 |
| Molecular Formula | C9H18NO |
| Molecular Weight | 156.25 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (100 mg/mL) or ethanol (100 mg/mL) |
| Source | Synthetic |
| Appearance | Purple Solid |
| SMILES | CC1(CCCC(N1[O])(C)C)C |
| InChI | InChI=1S/C9H18NO/c1-8(2)6-5-7-9(3,4)10(8)11/h5-7H2,1-4H3 |
| InChIKey | QYTDEUPAUMOIOP-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R34- Causes Burns Hazard Phrases: H314 Precautionary Phrases: P280-P305 + P351 + P338-P310 |
| Cite This Product | TEMPO (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-155) |
Biological Description
| Alternative Names | 2,2,6,6-Tetramethylpiperidine 1-oxyl, 2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical, (2,2,6,6-Tetramethyl-1-piperidinyl)oxidanyl, 1,1,5,5-tetramethylpentamethylene nitroxide, 2,2,6,6-Tetramethylpiperidine-1-oxyl |
| Research Areas | Cancer, Oxidative Stress |
| PubChem ID | 2724126 |
| Scientific Background | TEMPO (2,2,6,6-Tetramethylpiperidine 1-oxyl) is a stable nitroxide radical widely used as a spin label and redox probe in biological systems. In neuroscience, TEMPO has been explored for its antioxidant properties and ability to scavenge reactive oxygen species. Its membrane-permeable nature allows it to modulate oxidative stress in neuronal cells, potentially protecting against neurodegeneration. TEMPO derivatives have also been investigated for their role in reducing mitochondrial dysfunction and inflammation, key contributors to neurodegenerative pathology. |
| References | 1. Montanari F., Quici S., Henry-Riyad H., Tidwell T.T. (2005) Encyclopedia of Reagents for Organic Synthesis. John Wiley & Sons. |
Product Images
Chemical structure of TEMPO (SIH-155), a Stabilized free radical. CAS #: 2564-83-2. Molecular Formula: C9H18NO . Molecular Weight: 156.25 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.