TEMPO

Stable Nitroxyl Radical

Catalog No. SIH-155

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CAS No. 2564-83-2
Molecular Formula C9H18NO
SKU: SIH-155 Categories: ,

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SIH-155_TEMPO_Chemical_Structure.png
Product Name TEMPO
Description

Stable Nitroxyl Radical

Purity >98%
CAS No. 2564-83-2
Molecular Formula C9H18NO
Molecular Weight 156.25
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility May be dissolved in DMSO (100 mg/mL) or ethanol (100 mg/mL)
Source Synthetic
Appearance Purple Solid
SMILES CC1(CCCC(N1[O])(C)C)C
InChI InChI=1S/C9H18NO/c1-8(2)6-5-7-9(3,4)10(8)11/h5-7H2,1-4H3
InChIKey QYTDEUPAUMOIOP-UHFFFAOYSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R34- Causes Burns
Hazard Phrases:
H314
Precautionary Phrases:
P280-P305 + P351 + P338-P310
Cite This Product TEMPO (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-155)

Biological Description

Alternative Names 2,2,6,6-Tetramethylpiperidine 1-oxyl, 2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical, (2,2,6,6-Tetramethyl-1-piperidinyl)oxidanyl, 1,1,5,5-tetramethylpentamethylene nitroxide, 2,2,6,6-Tetramethylpiperidine-1-oxyl
Research Areas Cancer, Oxidative Stress
PubChem ID 2724126
Scientific Background TEMPO (2,2,6,6-Tetramethylpiperidine 1-oxyl) is a stable nitroxide radical widely used as a spin label and redox probe in biological systems. In neuroscience, TEMPO has been explored for its antioxidant properties and ability to scavenge reactive oxygen species. Its membrane-permeable nature allows it to modulate oxidative stress in neuronal cells, potentially protecting against neurodegeneration. TEMPO derivatives have also been investigated for their role in reducing mitochondrial dysfunction and inflammation, key contributors to neurodegenerative pathology.
References 1.  Montanari F., Quici S., Henry-Riyad H., Tidwell T.T. (2005) Encyclopedia of Reagents for Organic Synthesis. John Wiley & Sons.

Product Images

<p>Chemical structure of TEMPO (SIH-155), a Stabilized free radical. CAS #: 2564-83-2. Molecular Formula: C9H18NO . Molecular Weight: 156.25 g/mol.</p>

Chemical structure of TEMPO (SIH-155), a Stabilized free radical. CAS #: 2564-83-2. Molecular Formula: C9H18NO . Molecular Weight: 156.25 g/mol.

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