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| Product Name | UNC-2170 HCl |
| Description |
Methyl-lysine binding protein inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 1648707-58-7 |
| Molecular Formula | C14H21BrN2O • HCl |
| Molecular Weight | 349.7 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (40 mg/ml); or water (50 mg/ml) |
| Source | Synthetic |
| Appearance | White powder |
| Cite This Product | UNC-2170 HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-559) |
Biological Description
| Alternative Names | 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide, hydrochloride |
| Research Areas | Cell Signaling, DNA Damage and Repair, DNA/RNA, Epigenetics and Nuclear Signaling |
| Scientific Background | UNC-2170 HCl is a selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE1), a membrane protein involved in pH regulation and ion homeostasis. In neuroscience, NHE1 activity has been linked to excitotoxicity, neuroinflammation, and blood-brain barrier disruption. UNC-2170 HCl is used to study the role of NHE1 in ischemic brain injury, traumatic brain injury, and neurodegenerative diseases. By modulating intracellular pH and ion flux, it offers insights into mechanisms of neuronal injury and potential neuroprotective strategies. |
Product Images
Chemical structure of UNC-2170 HCl (SIH-559), a Methyl-lysine binding protein inhibitor. CAS #: 1648707-58-7. Molecular Formula: C14H21BrN2O • HCl. Molecular Weight: 349.7 g/mol.
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