Discovery through Partnership | Excellence through Quality
| Product Name | Lysophosphatidic Acid, Sodium Salt |
| Description |
Autophagy inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 22556-62-3 |
| Molecular Formula | C21H40O7P*Na |
| Molecular Weight | 458.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (1 mg/ml) and warm water (10 mg/ml). |
| Source | Synthetic |
| Appearance | White powder. |
| SMILES | C(O[P](=O)(O)O)C(O)COC(=O)CCCCCCCC=C/CCCCCCCC |
| InChI | InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1 |
| InChIKey | WRGQSWVCFNIUNZ-GDCKJWNLSA-N |
| Safety Phrases |
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Lysophosphatidic Acid, Sodium Salt (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-403) |
Biological Description
| Alternative Names | Oleoyl-lysophosphatidic acid sodium salt |
| Research Areas | Autophagy, Cancer |
| PubChem ID | 23688917 |
| Scientific Background | Lysophosphatidic acid (LPA) is a bioactive lipid that acts through G-protein-coupled receptors to regulate cell proliferation, migration, and survival. In neuroscience, LPA signaling is implicated in neurodevelopment, synaptic plasticity, and neuroinflammation. Dysregulation of LPA pathways has been associated with neurodegenerative diseases and traumatic brain injury. Sodium salt forms of LPA are used in experimental models to study receptor-mediated signaling and its impact on neuronal and glial cell function. LPA’s role in modulating neuroimmune interactions and promoting neural regeneration makes it a key molecule in neurobiology research. |
| References |
1. van Corven E.J., et al. (1992) Biochem J. 281(Pt 1): 163-9. 2. Chang C.L., et al. (2007) Autophagy. 3(3): 268-70. |
Product Images
Chemical structure of Lysophosphatidic Acid (SIH-403), a Autophagy inhibitor. CAS #: 22556-62-3 . Molecular Formula: C21H40O7P. Molecular Weight: 436.5245 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.