Discovery through Partnership | Excellence through Quality
| Product Name | P7C3 |
| Description |
NAMPT activator |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 301353-96-8 |
| Molecular Formula | C21H18Br2N2O |
| Molecular Weight | 474.2 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Activator |
| Solubility | May be dissolved in DMSO (40 mg/ml) |
| Source | Synthetic |
| Appearance | Off-white powder |
| SMILES | BrC(C=C3)=CC1=C3N(CC(O)CNC4=CC=CC=C4)C2=C1C=C(Br)C=C2 |
| InChI | InChI=1S/C21H18Br2N2O/c22-14-6-8-20-18(10-14)19-11-15(23)7-9-21(19)25(20)13-17(26)12-24-16-4-2-1-3-5-16/h1-11,17,24,26H,12-13H2 |
| InChIKey | FZHHRERIIVOATI-UHFFFAOYSA-N |
| Safety Phrases |
Hazard Statements: H301 (100%): Toxic if swallowed H318 (100%): Causes serious eye damage Precautionary Statements: P264, P270, P280, P301+P310, P305+P351+P338, P310, P321, P330, P405, and P501 |
| Cite This Product | P7C3 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-571) |
Biological Description
| Alternative Names | 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol; AK34095 |
| Research Areas | Alzheimer's Disease, Angiogenesis, Apoptosis, Atherosclerosis, Cancer, Cardiovascular Growth Factors, Cardiovascular System, Cell Cycle, Diabetes Associated, Neurodegeneration, Neuroscience, p53 Pathway, VEGF, VEGF Receptors |
| PubChem ID | 2836187 |
| Scientific Background | P7C3 is a neuroprotective compound that promotes neuronal survival by preventing apoptosis of newborn neurons. It has demonstrated efficacy in preserving cognitive function in aged animals and in models of neurodegenerative diseases such as ALS, Parkinson’s disease, and Down syndrome. P7C3 acts by activating nicotinamide phosphoribosyltransferase (NAMPT), leading to increased intracellular NAD⁺ levels. Its ability to enhance neurogenesis and protect against neuronal loss makes it a promising candidate for therapeutic development in neurodegeneration. |
Product Images
Chemical structure of P7C3 (SIH-571), a NAMPT activator. CAS #: 301353-96-8. Molecular Formula: C21H18Br2N2O. Molecular Weight: 474.2 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.