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| Product Name | RK-682 |
| Description |
Protein Tyrosine Phosphatase Inhibitor |
| Purity | >98% (HPLC) |
| CAS No. | 150627-37-5 |
| Molecular Formula | C21H36O5 |
| Molecular Weight | 368.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble DMSO, heptane and xylene: ≥8 mg/ml |
| Source | Synthetic |
| Appearance | Solid |
| InChI | InChI=1S/C21H36O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(23)19-20(24)18(16-22)26-21(19)25/h18,22,24H,2-16H2,1H3 |
| InChIKey | KZTSLHQKWLYYAC-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | RK 682 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-522) |
Biological Description
| Alternative Names | RK-682, (R)-3-Hexadecanoyl-5-hydroxymethyltetronic acid, (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone |
| Research Areas | Cell Signaling |
| PubChem ID | 54685915 |
| Scientific Background | RK 682 is a naturally derived inhibitor of protein tyrosine phosphatases, known for its ability to arrest cell cycle progression at the G1 phase. While its primary applications have been in cancer and immunology, RK 682's modulation of phosphatase activity has relevance in neuroscience, particularly in the regulation of neuronal signaling and synaptic plasticity. Protein tyrosine phosphatases are involved in neurodevelopment and neurodegenerative processes, making RK 682 a useful probe for studying phosphatase-mediated pathways in neuronal health and disease. |
| References | 1. Hamaguchi T., Sudo T., & Osada H. (1995) FEBS Letters. 372(1): 54–58. |
Product Images
Chemical structure of RK 682 (SIH-522), a Tyrosine phopshatase inhibitor. CAS #: 150627-37-5. Molecular Formula: C21H36O5. Molecular Weight: 368.5 g/mol.
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