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| Product Name | SB-366791 |
| Description |
TRPV1 blocker |
| Purity | >98% |
| CAS No. | 472981-92-3 |
| Molecular Formula | C16H14CINO2 |
| Molecular Weight | 287.75 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 10 mM in ethanol and to 100 mM in DMSO |
| Source | Synthetic |
| Appearance | White solid |
| SMILES | COC1=CC=CC(=C1)NC(=O)/C=C/C2=CC=C(C=C2)Cl |
| InChI | InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ |
| InChIKey | RYAMDQKWNKKFHD-JXMROGBWSA-N |
| Safety Phrases |
Classification: Caution: Substance not fully tested yet. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes |
| Cite This Product | SB-366791 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-321) |
Biological Description
| Alternative Names | (2E)-3-(4-Chlorophenyl)-N-(3-methoxyphenyl)acrylamide, N-(3-Methoxyphenyl)-4-chlorocinnamide |
| Research Areas | Ion Channels, Neuroscience |
| PubChem ID | 667594 |
| Scientific Background | A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat. |
| References | 1. Gunthorpe M.J., et al. (2004) Neuropharmacology. 46(1): 133-149. |
Product Images
Chemical structure of SB-366791 (SIH-321), a TRPV1 blocker. CAS #: 472981-92-3. Molecular Formula: C16H14CINO2. Molecular Weight: 287.75 g/mol.
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