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| Product Name | Carboxy-PTIO Potassium salt |
| Description |
Nitric Oxide Scavenger |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 148819-94-7, 148819-94-8, 148819-94-9 |
| Molecular Formula | C14H16KN2O4 |
| Molecular Weight | 315.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Scavenger |
| Solubility | May be dissolved in water (100 mg/ml) |
| Source | Synthetic |
| Appearance | Blue powder |
| SMILES | CC1(C([N+](=C(N1[O])C2=CC=C(C=C2)C(=O)[O-])[O-])(C)C)C.[K+] |
| InChI | InChI=1S/C14H17N2O4.K/c1-13(2)14(3,4)16(20)11(15(13)19)9-5-7-10(8-6-9)12(17)18;/h5-8H,1-4H3,(H,17,18);/q;+1/p-1 |
| InChIKey | VYEUQMVIGXFZQU-UHFFFAOYSA-M |
| Safety Phrases | Not a hazardous substance or mixture. |
| Cite This Product | Carboxy-PTIO Potassium salt (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-594) |
Biological Description
| Alternative Names | 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, potassium salt |
| Research Areas | Neuroscience, Neurotransmission, Nitric Oxide |
| PubChem ID | 2733502 |
| Scientific Background | Carboxy-PTIO Potassium salt is a nitric oxide (NO) scavenger widely used in biochemical and physiological studies to modulate NO signaling. It serves as a monitor of NO levels, a stoichiometric source of nitrogen dioxide (NO2), and a tool for eliminating NO in experimental systems. In neuroscience, Carboxy-PTIO is employed to investigate the role of NO in synaptic plasticity, neuroinflammation, and oxidative stress. Its ability to modulate NO pathways makes it valuable in neurodegenerative disease research, particularly in models of stroke, Parkinson’s disease, and Alzheimer’s disease. |
| References | 1. Goldstein S., Russo A., Samuni A. (2003) Mechanism Signal Transduction. 278 (51): P50949-50955. |
Product Images
Chemical structure of Carboxy-PTIO Potassium salt (SIH-594), a Nitric Oxide Scavenger. CAS #: . Molecular Formula: C14H16KN2O4. Molecular Weight: 315.4 g/mol.
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