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| Product Name | SMI-4a |
| Description |
ATP-competitive Pim kinase inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 438190-29-5 |
| Molecular Formula | C11H6F3NO2S |
| Molecular Weight | 273.23 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (100 mg/ml); or Ethanol (40 mg/ml, warm) |
| Source | Synthetic |
| Appearance | Tan solid |
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2 |
| InChI | InChI=1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5- |
| InChIKey | NGJLOFCOEOHFKQ-YVMONPNESA-N |
| Safety Phrases |
Hazard statements: H317 - May cause an allergic skin reaction H319 - Causes serious eye irritation Precautionary Statements: P261 - Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray P264 - Wash face, hands and any exposed skin thoroughly after handling P272 - Contaminated work clothing should not be allowed out of the workplace P280 - Wear protective gloves/ protective clothing/ eye protection/ face protection P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P333 + P313 - If skin irritation or rash occurs: Get medical advice/ attention P337 + P313 - If eye irritation persists: Get medical advice/ attention P362 - Take off contaminated clothing and wash before reuse |
| Cite This Product | SMI-4a (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-572) |
Biological Description
| Alternative Names | 5-(3-Trifluoromethylbenzylidene)thiazolidine-2,4-dione |
| Research Areas | Apoptosis, Cancer, Cell Signaling, Other Kinases, Protein Phosphorylation |
| PubChem ID | 1361334 |
| Scientific Background | Selective inhibitor of Pim-1 and Pim-2 protein kinases. |
Product Images
Chemical structure of SMI-4a (SIH-572), a ATP-competitive Pim kinase inhibitor. CAS #: 438190-29-5. Molecular Formula: C11H6F3NO2S. Molecular Weight: 273.23 g/mol.
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