Discovery through Partnership | Excellence through Quality
| Product Name | SU1498 |
| Description |
VEGFR kinase inhibitor |
| Purity | >98% |
| CAS No. | 168835-82-3 |
| Molecular Formula | C25H30N2O2 |
| Molecular Weight | 390.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO |
| Source | Synthetic |
| Appearance | Solid |
| SMILES | CC(C)C1=CC(=CC(=C1O)C(C)C)/C=C(C#N)/C(=O)NCCCC2=CC=CC=C2 |
| InChI | InChI=1S/C25H30N2O2/c1-17(2)22-14-20(15-23(18(3)4)24(22)28)13-21(16-26)25(29)27-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-15,17-18,28H,8,11-12H2,1-4H3,(H,27,29)/b21-13+ |
| InChIKey | JANPYFTYAGTSIN-FYJGNVAPSA-N |
| Safety Phrases |
Classification: Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity -single exposure (Category 3), Respiratory system, H335 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statements: P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P321 Specific treatment (see supplemental first aid instructions on this label). P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. |
| Cite This Product | SU1498 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-480) |
Biological Description
| Alternative Names | (E)-N-(3″-Phenylpropyl)-α-cyano-3′,5′-diisopropyl-4′-hydroxycinnamamide, Tyrphostin SU 1498 |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 5941539 |
| Scientific Background | SU1498 is a potent and selective inhibitor of Flk-1, a VEGF receptor kinase, and VEGFR2. |
| References |
1. Kisielewska J., Ligeza J., & Klein A. (2008) Folia Histochemica Et Cytobiologica. 46(2): 185–191. 2. Cebulla C.M., et al. (2008) Ophthal J. 2: 62–67. |
Product Images
Chemical structure of SU1498 (SIH-480), a VEGFR kinase inhibitor. CAS #: 168835-82-3. Molecular Formula: C25H30N2O2. Molecular Weight: 390.5 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.