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| Product Name | Vandetanib |
| Description |
VEGFRK inhibitor |
| Purity | >98% (HPLC) |
| CAS No. | 443913-73-3 |
| Molecular Formula | C22H24BrFN4O2 |
| Molecular Weight | 475.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (30 mg/ml) or EtOH (10 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow solid |
| SMILES | C1=C3C(=CC(=C1OC)OCC2CCN(CC2)C)N=CN=C3NC4=CC=C(Br)C=C4F |
| InChI | InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) |
| InChIKey | UHTHHESEBZOYNR-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Vandetanib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-483) |
Biological Description
| Alternative Names | N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Growth Factor Receptor Inhibitors |
| PubChem ID | 3081361 |
| Scientific Background | Vandetanib is a specific inhibitor of Flk-1 and Flt-4. |
| References | 1. Bruns C.J., et al. (2000) Clin. Cancer. Res: J. Am. Assoc. Cancer Res. 6(5): 1936–1948. |
Product Images
Chemical structure of Vandetinib (SIH-483), a VEGFRK inhibitor. CAS #: 443913-73-3. Molecular Formula: C22H24BrFN4O2. Molecular Weight: 475.4 g/mol.
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