Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Piperlongumine
Catalog #: SIH-156-100MG
Size: 100mg
Type: Inhibitor
Description: Apoptosis inducer in oxidative stressed cells
Research Area: Oxidative Stress
CAS Number: 20069-09-4
Formula: C17H19NO5
Molecular weight: 317.3
Source/Host: Synthetic
Purity: >98%
Solubility: May be dissolved in 25mg/mL of DMSO
Appearance: Cream Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases: H302
Datasheet: SIH 156 Piperlongumine Oxidative Stress Inhibitor
Price: $299.00 USD Add to Cart Bulk Quote

Structure of Piperlongumine

Research Background: Piperlongumine is a novel compound that exhibits a potential inhibitory effect on washed rabbit platelet aggregation induced by collagen, arachidonic acid and platelet activating factor, without any inhibiting effect on that induced by thrombin (1). It has recently been found to kill cancer cells by blocking the response that dissipates high oxidative stress and the resulting reactive oxygen species (ROS) generated, meanwhile sparing normal cells (2).
References: 1. Park B.S., et al. (2008) Phytother Res. 22(9): 1195-1199.
2. Raj L., et al. (2011) Nature. 475(7355): 231.

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