Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Andrographolide
Catalog #: SIH-220-500MG
Size: 500mg
Type: Inducer
Description: Induces mitochondrial -mediated apoptosis in lymphoma cells
Research Area: Apoptosis
CAS Number: 5508-58-7
Formula: C20H30O5
Molecular weight: 350.45
Source/Host: Synthetic
Purity: >99%
Solubility: DMSO
Appearance: Off-white solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Caution: Substance not yet fully tested.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Datasheet: SIH 220 Andrographolide Apoptosis Inducer
Price: $135.00 USD Add to Cart Bulk Quote

Structure of Andrographolide

Research Background: Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Is has been shown to be effective against certain cancers, and is an effective purgative (1). It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement (2, 3).
References: 1. Chakravarti R.N., Chakravarti D. (1951) Ind. Med Gaz. 86(3): 96-7.
2. Tsai H.R., et al. (2004) Eur J Pharmacol. 498: 45-52.
3. Rajagopal S., et al. (2003) J Exp. Ther. Oncol. 3: 147-158.

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