Valinomycin

Apoptosis Inducer

Catalog No. SIH-230

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CAS No. 2001-95-8
Molecular Formula C54H90N6O18
SKU: SIH-230 Categories: ,

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SIH-230_Valinomycin_Chemical_Structure.png
Product Name Valinomycin
Description

Apoptosis Inducer

Purity >98%
CAS No. 2001-95-8
Molecular Formula C54H90N6O18
Molecular Weight 1111.32
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inducer
Solubility Soluble to 25 mM in DMSO and 25 mM in ethanol.
Source Synthetic
Appearance White Solid
SMILES C[C@H]1C(=O)N[C@H](C(=O)O[C@@H](C(=O)N[C@@H](C(=O)O[C@H](C(=O)N[C@H](C(=O)O[C@@H](C(=O)N[C@@H](C(=O)O[C@H](C(=O)N[C@H](C(=O)O[C@@H](C(=O)N[C@@H](C(=O)O1)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C)C)C(C)C)
InChI InChI=1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(
InChIKey FCFNRCROJUBPLU-UYBNATROSA-N
Safety Phrases Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R68 - Possible risk of irreversible effects
Hazard Phrases:
H300-H310
Precautionary Phrases:
P264-P280-P302 + P350-P310
Cite This Product Valinomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-230)

Biological Description

Alternative Names (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone
Research Areas Apoptosis, Cancer
PubChem ID 5649
Scientific Background Valinomycin is a dodecadepsipeptide, and a member of a group of natural neutral ionophores. It is highly selective for potassium ions within the cell membrane (1). It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes down an electrochemical potential gradient (2).
References 1. Lars R., Jenkins A.T.A. (2007) Bioelectrochem. 70(2): 387-393.
2. Cammann K. (1985) Top Curr Chem. 128: 219-258.

Product Images

<p>Chemical structure of Valinomycin (SIH-230), a Induces loss of mitochondrial membrane potential. CAS #: 2001-95-8. Molecular Formula: C54H90N6O18. Molecular Weight: 1111.32 g/mol.</p>

Chemical structure of Valinomycin (SIH-230), a Induces loss of mitochondrial membrane potential. CAS #: 2001-95-8. Molecular Formula: C54H90N6O18. Molecular Weight: 1111.32 g/mol.

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