Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Fumonisin B1
Catalog #: SIH-234-5MG
Size: 5mg
Type: Inducer
Description: Blocks sphingolipid biosynthesis
Research Area: Apoptosis
CAS Number: 116355-83-0
Formula: C34H59NO15
Molecular weight: 721.83
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 10mM in DMSO.
Appearance: Beige Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
R60- May impair fertility
R61- May cause harm to the unborn child

Hazard Phrases: H351

Precautionary Phrases: P281
Datasheet: SIH 234 Fumonisin B1 Apoptosis Inducer
Price: $264.00 USD Add to Cart Bulk Quote

Structure of Fumonism B1

Research Background: Fumonisin B1 is the most prevalent member of a family of toxins. It is hepatotoxic and nephrotoxic in all animal species. It occupies the space and electrostatic interactions of both sphinganine and fatty acyl-CoA (1). Due to this mechanism of action, it has toxic effects in humans such as neural tube defects (2), esophageal cancer, acute mycotoxicosis, and various other carcinogenic effects. Another effect of exposure to FB1 is apoptosis (2).
References: 1. European commission (2007). “Fumonisin B1”. Opinion of the scientific committee on food on Fusarium toxins (27).
2. Stockmann-Juvalla H., and Savolainen K. (2008) Human and Exp. Toxicology. 27:799-809.

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