Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Etoposide
Catalog #: SIH-244-500MG
Size: 500mg
Type: Inducer
Description: Topoisomerase II inhibitor
Research Area: Apoptosis
CAS Number: 33419-42-0
Formula: C29H32O13
Molecular weight: 588.56
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO.
Appearance: White solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S53 - Avoid exposure - obtain special instruction before use

Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed
R45 - May cause cancer
R62 - Possible risk of impaired fertility
R68 - Possible risk of irreversible effects

Hazard Phrases: H302-H350

Precautionary Phrases: P201-P308 + P313
Datasheet: SIH 244 Etoposide Apoptosis Inducer
Price: $279.00 USD Add to Cart Bulk Quote

Structure of Etoposide

Research Background: Etoposide inhibits the enzyme topoisomerase II, which unwinds DNA, and be doing so causes the DNA strand to break. Cancer cells are then less likely to be able to repair this damage (1).
References: 1. Gordaliza M., et al. (2004) Toxicon. 44(4): 441-459.

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