Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Dexamethasone
Catalog #: SIH-259-5G
Size: 5g
Type: Inducer
Description: Apoptosis inducing glucocorticoid
Research Area: Apoptosis
CAS Number: 50-02-2
Formula: C22H29FO5
Molecular weight: 392.47
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO
Appearance: White solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases: R62 - Possible risk of impaired fertility
R68- Possible risk of irreversible effects

Hazard Phrases: H315-H317-H319-H334-H335

Precautionary Phrases: P261-P280-P305 + P351 + P338-P342 + P311
Datasheet: SIH 259 Dexamethasone Apoptosis Inducer
Price: $219.00 USD Add to Cart Bulk Quote

Structure of Dexamethasone

Research Background: Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It is an anti-inflammatory and immunosuppressant. In cancer patients, it can be give to augment the antiemetic effect of 5-HT3 receptor antagonists, and is also used to counteract the development of edema (1). In a diagnostic setting, it is used to suppress the natural pituitary-adrenal axis (2).
References: 1. Roila F., and Fatigoni S. (2006) Ann Oncol.17 (Suppl2): ii96-ii100.
2. Hasan E.A., Jessop D.S., Power L.L. Monk P.T. and Kirwan J.R. (2009) Int J Endocrinol. 2009: 391284.

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