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| Product Name | SL-01 |
| Description |
p53/mdm2 inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 26049-94-5 |
| Molecular Formula | C18H18ClNO3 |
| Molecular Weight | 331.8 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in 50 mg/ml DMSO oir 15 mg/ml warm Ethanol |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | C1=CC=C(C=C1)C[C@@H](C(=O)CCl)NC(=O)OCC2=CC=CC=C2 |
| InChI | InChI=1S/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)/t16-/m0/s1 |
| InChIKey | OYHLRJGDELITAF-INIZCTEOSA-N |
| Safety Phrases |
Classification: Caution – Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes |
| Cite This Product | SL-01 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-343) |
Biological Description
| Alternative Names | Benzyl [(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]carbamate; N-Benzyloxycarbonyl-Lphenylalaninylchloromethyl ketone; ZPCK |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, p53/mdm2 Inhibitors |
| PubChem ID | 99625 |
| Scientific Background | Inhibits the p53-MDM2 interaction (20 µM). Has also been shown to inhibit bovine chymotrypsin A-y. |
| References | 1. Li J., et al. (2011) J Biol Screening 16: 450. |
Product Images
Chemical structure of SL-01 (SIH-343), a p53/mdm2 inhibitor. CAS #: 26049-94-5. Molecular Formula: C18H18ClNO3. Molecular Weight: 331.8 g/mol.
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