BML-278 SIRT1 activator

SIRT1 activator

Catalog No. SIH-349

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Molecular Forumla C24H25NO4

USD $67.00USD $273.00

SKU: SIH-349 Categories: , .

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Product Name BML-278 SIRT1 activator

SIRT1 activator

Purity >98% (TLC); NMR (Conforms)
Molecular Formula C24H25NO4
Molecular Weight 391.5


Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in 5 mg/ml DMSO
Source Synthetic
Appearance Off-White Solid
Safety Phrases Classification: Caution – Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Cite This Product Bml-278 SIRT1 activator (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-349)

Biological Description

Alternative Names N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
Research Areas Cell Signaling, Epigenetics
Scientific Background A structurally novel activator of SIRT1 (EC150=1 µM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 µM respectively). Cell permeable.
References 1. Mai A., et al. (2009) J. Med. Chem. 52: 5496.

Product Images

Chemical structure of BML-278 SIRT1 activator (SIH-349), a SIRT1 activator. CAS #: N/A. Molecular Formula: C24H25NO4. Molecular Weight: 391.5 g/mol.

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