Products

  • Anti-GFAP R416WT Antibody [N206B/9 (Formerly sold as S206B-9)]

    Mouse Anti-Human GFAP R416WT Monoclonal IgG1

    Catalog No. SMC-442

    0 out of 5 based on 0 customer ratings
    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-442 Categories: ,

    SMC-442_GFAP-R416WT_Antibody_N206B-9_ICC-IF_Human_Neuroblastoma-cells-SH-SY5Y-Composite-1.png
    Mouse Anti-GFAP R416WT Antibody [N206B/9] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Neuroblastoma cell line (SK-N-BE) (SMC-442)Mouse Anti-GFAP Antibody [N206B/9] used in Western Blot (WB) on Rat Brain Membrane (SMC-442)
  • Anti-ENaC alpha Antibody

    Rabbit Anti-Rat ENaC alpha Polyclonal

    Catalog No. SPC-403

    4.75 out of 5 based on 4 customer ratings
    Species Reactivity Hu, Rt, Ms, Xe
    Applications WB IHC ICC/IF FCM IP
    SKU: SPC-403 Categories: ,

    SPC-403_ENaC_Antibody_IHC_Rat_kidney-tissue_63X_1.png
    Rabbit Anti-ENaC Antibody used in Western blot (WB) on kidney tissue lysates (SPC-403)Rabbit Anti-ENaC Antibody used in Western blot (WB) on kidney tissue lysates (SPC-403)
  • RECOMBINANT Anti-SHANK3 Antibody [S69]

    Mouse Anti-Rat SHANK3 Monoclonal IgG2b

    Catalog No. SMC-336

    5.00 out of 5 based on 1 customer rating
    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-336 Categories: ,

    SMC-336_SHANK3_Antibody_S69_ICC-IF_Human_Neuroblastoma-cells-SH-SY5Y-Composite-1.png
    Mouse Anti-SHANK3 Antibody [S69] used in Immunohistochemistry (IHC) on Mouse backskin (SMC-336)Mouse Anti-SHANK3 Antibody [S69] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human HaCaT cells (SMC-336)Mouse Anti-SHANK3 Antibody [S69] used in Western Blot (WB) on Rat brain membrane lysate (SMC-336)
  • Anti-ENaC beta Antibody

    Rabbit Anti-Rat ENaC beta Polyclonal

    Catalog No. SPC-404

    4.00 out of 5 based on 3 customer ratings
    Species Reactivity Hu, Ms, Rt, Xe, Hm
    Applications WB IHC ICC/IF FCM IP
    SKU: SPC-404 Categories: ,

    SPC-404_ENaC_Antibody_IHC_Rat_kidney-tissue_1.png
    Rabbit Anti-ENaC Antibody used in Western blot (WB) on kidney tissue lysates (SPC-404)Rabbit Anti-ENaC Antibody used in Western blot (WB) on mpkCCD cell lysates (SPC-404)Rabbit Anti-ENaC Antibody used in Western blot (WB) on kidney cortex (SPC-404)
  • RECOMBINANT Anti-HCN2 Antibody [S71]

    Mouse Anti-Rat HCN2 Monoclonal IgG1

    Catalog No. SMC-305

    5.00 out of 5 based on 1 customer rating
    Species Reactivity Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-305 Categories: ,

    This product is currently out of stock and unavailable. Notify me when this product is available.

    SMC-305_HCN2_Antibody_S71_IHC_mouse_frozen-brain-section_1.png
    Mouse Anti-HCN2 Antibody [S71] used in Western Blot (WB) on Rat brain membrane lysate (SMC-305)Mouse Anti-HCN2 Antibody [S71] used in Western Blot (WB) on Mouse Brain (SMC-305)
  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 2)

    Catalog No. SPR-316

    0 out of 5 based on 0 customer ratings
    Expression System E. coli
    Tags No tag
    SKU: SPR-316 Category:

    SPR-316_Alpha-Synuclein-Protein-Monomer-Protein-SDS-Page-1.png
    Alpha Synuclein monomers (SPR-316) do not form new alpha synuclein fibrils when combined with Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by a limited increase in fluorescence intensity by Thioflavin T over time.Alpha Synuclein Monomer RT-QuiC AssayΑlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.LDH assay shows effect of alpha synuclein monomers on mouse primary neuronsMTT assay shows effects of alpha synuclein monomers on mouse primary neurons
  • Alpha Synuclein Pre-formed Fibrils

    Human Recombinant Alpha Synuclein PFFs (Type 2)

    Catalog No. SPR-317

    5.00 out of 5 based on 2 customer ratings
    Expression System E. coli
    Tags No tag
    SKU: SPR-317 Category:

    SPR-317_Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-4.png
    TEM of Type 2 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-317)Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.SDS-Page of Type 2 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-317)Type 2 alpha synuclein Pre-formed fibrils (SPR-317) do not seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) at the same rate as Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by lower fluorescence intensity values of Thioflavin T over time.Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)LDH assay shows effect of alpha synuclein PFFs on mouse primary neuronsMTT assay effects of alpha synuclein PFFs on mouse primary neurons
  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-321

    5.00 out of 5 based on 1 customer rating
    Expression System E. coli
    Tags No tag
    SKU: SPR-321 Category:

    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)
  • Alpha Synuclein Pre-formed Fibrils

    Human Recombinant Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-322

    5.00 out of 5 based on 1 customer rating
    Expression System E. coli
    Tags No tag
    SKU: SPR-322 Category:

    SPR-322_Alpha-Synuclein-Protein-Preformed-Fibrils-Protein-TEM-7.png
    Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.ICC/IF of human Alpha Synuclein Protein Preformed Fibrils Protein (SPR-322)ICC/IF of human Alpha Synuclein Protein Preformed Fibrils Protein (SPR-322)StressMarq’s Alpha Synuclein PFFs (red) cat#SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days.SDS-Page of Type 1 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-322)Type 1 alpha synuclein Pre-formed fibrils (SPR-322) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) as shown by increased fluorescence intensity by Thioflavin T over time.Immunocytochemistry/Immunofluorescence of Human Alpha Synuclein Protein Protein (SPR-322)Mouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFsMouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFs cause endogenous alpha synuclein phosphorylationTEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-322)IHC of Sprague-Dawley rat brain injected with Type 1 human alpha synuclein Pre-formed fibrils (SPR-322)Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).
  • Alpha Synuclein Pre-formed Fibrils: ATTO 594

    Human Recombinant Alpha Synuclein PFFs: ATTO 594 (Type 1)

    Catalog No. SPR-322-A594

    5.00 out of 5 based on 1 customer rating
    Expression System E. coli
    Tags ATTO 594
    SKU: SPR-322-A594 Category:

    SPR-322-A594_Alpha-Synuclein-Protein-Protein-TEM-1.png
    Thioflavin T Assay for SPR-322-A594Human iPSC-derived neurons seeded with ATTO594 labelled alpha synuclein PFFs (SPR-322-A594)TEM of ATTO conjugated alpha syuclein pre-formed fibrils