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  • Alpha Synuclein Pre-formed Fibrils

    Mouse Recombinant Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-324

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    Expression System E. coli
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    SPR-324_Alpha-Synuclein-Protein-Preformed-Fibrils-ICC-IF-1.png
    IHC of mouse brain injected with alpha synuclein monomers and fibrilsIHC of mouse brain injected with alpha synuclein monomers and fibrilsIHC of Sprague-Dawley rat brain injected with Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324)Mouse hippocampal neurons treated with mouse alpha synuclein PFFs show phosphorylationTEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324).Mouse Type 1 alpha synuclein Pre-formed Fibrils (SPR-324) seed the formation of new alpha Synuclein fibrils from the pool of alpha synuclein monomers (SPR-323) as shown by increased fluorescence intensity by Thioflavin T over time.TEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324).SDS-Page of Type 1 Mouse Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-324)

  • Alpha Synuclein Monomers

    Mouse Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-321

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    Expression System E. coli
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    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs: ATTO 488

    Catalog No. SPR-329-A488

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    Expression System E. coli
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    SPR-329-A488_Tau-Protein-Protein-TEM-1.png
    TEM of ATTO conjugated tau pre-formed fibrilsThioflavin T assay of ATTO-488 conjugated tau fibrils

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs

    Catalog No. SPR-329

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    Expression System E. coli
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    SPR-329_Tau-Protein-Peformed-Fibrils-TEM-1.png
    TEM of recombinant Tau441 (2N4R), P301S mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) when tau Pre-formed fibrils (SPR-329) are combined with tau monomers (SPR-327). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.SDS-PAGE of ~67 kDa Human Tau 2N4R P301S Pre-formed Fibrils (PFFs)

  • Tau (K18) P301L Mutant Pre-formed Fibrils

    Human Recombinant Tau (K18) P301L Mutant PFFs

    Catalog No. SPR-330

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    Expression System E. coli
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    SPR-330_Tau-Preformed-Fibrils-Protein-IHC-1.png
    Comparison of AT8 (pSer202/pThr205) tau inclusions in P301L mice injected with K18 PFFs and negative control.TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau Pre-formed fibrils (SPR-330). Tau Pre-formed fibrils (SPR-330) seed the formation of new tau fibrils when combined with tau monomers (SPR-327)SDS-PAGE of ~15 kDa Human Tau Protein K18/P301L Pre-formed Fibrils (SPR-330)

  • Tau (K18) P301L Mutant Monomers

    Human Recombinant Tau (K18) P301L Mutant Monomers

    Catalog No. SPR-328

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    SPR-328_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) in tau K18 P301L monomers (SPR-328) over time.

  • Alpha Synuclein N-Terminal Acetylated Pre-formed Fibrils

    Human Recombinant N-Terminal Acetylated Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-332

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    Expression System E. coli
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    SPR-332_N-Terminal-Acetylated-Alpha-Synuclein-Fibril-Protein-TEM-1.png
    TEM of N-acetylated alpha synuclein PFFsThioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (SPR-332)

  • Alpha Synuclein N-Terminal Acetylated Monomers

    Human Recombinant N-Terminal Acetylated Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-331

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    SPR-331_N-Terminal-Acetylated-Alpha-Synuclein-Monomer-Protein-Western-Blot-1.png
    Thioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Monomers (SPR-331)

  • Gamma Synuclein Monomers

    Human Recombinant Gamma Synuclein Monomers

    Catalog No. SPR-407

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    Expression System E. coli
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    SPR-407_Gamma-Synuclein-Monomer-Protein-Thioflavin-T-assay-1.png
    Coomassie gel stain of gamma synuclein monomer (SPR-407)