Products

  • Rasagiline mesylate

    MAO inhibitor

    Catalog No. SIH-577

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    CAS No. 161735-79-1
    Molecular Formula C12H13N • CH3SO3H
    SKU: SIH-577 Categories: ,

    SIH-577-Rasagiline-mesylate-Chemical-Structure.png

  • STO 609

    CAMKK kinase inhibitor

    Catalog No. SIH-479

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    CAS No. 1173022-21-3
    Molecular Formula C19H10N2O3·CH3COOH
    SKU: SIH-479 Categories: ,

    SIH-479_STO-609_Chemical_Structure.png

  • bis-BHT

    Phenolic antioxidant

    Catalog No. SIH-154

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    CAS No. 118-82-1
    Molecular Formula C29H44O2
    SKU: SIH-154 Categories: ,

    SIH-154_bis-BHT_Chemical_Structure.png

  • 6BIO

    PDK1 kinase inhibitor

    Catalog No. SIH-422

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    CAS No. 667463-62-9
    Molecular Formula C16H10BrN3O2
    SKU: SIH-422 Categories: ,

    SIH-422_6BIO_Chemical_Structure.png

  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 2)

    Catalog No. SPR-316

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    Expression System E. coli
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    SKU: SPR-316 Category:

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    SPR-316_Alpha-Synuclein-Protein-Monomer-Protein-SDS-Page-1.png
    Alpha Synuclein monomers (SPR-316) do not form new alpha synuclein fibrils when combined with Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by a limited increase in fluorescence intensity by Thioflavin T over time.Alpha Synuclein Monomer RT-QuiC AssayΑlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.LDH assay shows effect of alpha synuclein monomers on mouse primary neuronsMTT assay shows effects of alpha synuclein monomers on mouse primary neurons

  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-321

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)

  • Alpha Synuclein Monomers

    Mouse Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein A53T Mutant Monomers

    Human Recombinant Alpha Synuclein A53T Mutant Monomers (Type 1)

    Catalog No. SPR-325

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    Expression System E. coli
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    SPR-325_A53T-Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.Cisbio Total Alpha Synuclein AssayCisbio Alpha Synuclein Aggregation Assay

  • Alpha Synuclein A53T Mutant Pre-formed Fibrils

    Human Recombinant Alpha Synuclein A53T Mutant PFFs (Type 1)

    Catalog No. SPR-326

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    Expression System E. coli
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    SPR-326_A53T-Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-2.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.ICC/IF of human A53T Alpha Synuclein Preformed Fibrils Protein (SPR-326)ICC/IF of human A53T Alpha Synuclein Preformed Fibrils Protein (SPR-326)ICC of primary rat neurons treated with A53T alpha synuclein PFFs show Lewy body inclusion formation.Cisbio Alpha Synuclein Aggregation AssayCisbio Total Alpha Synuclein AssayLDH assay shows effect of A53T alpha synuclein PFFs on mouse primary neuronsMTT assay effects of A53T alpha synuclein PFFs on mouse primary neuronsTEM of A53T alpha synuclein pre-formed fibrils (SPR-326).

  • Tau (K18) P301L Mutant Monomers

    Human Recombinant Tau (K18) P301L Mutant Monomers

    Catalog No. SPR-328

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    Expression System E. coli
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    SPR-328_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) in tau K18 P301L monomers (SPR-328) over time.