10074-G5

c-Myc inhibitor

Catalog No. SIH-609

5.00 out of 5 based on 1 customer rating
CAS No. 413611-93-5
Molecular Formula C18H12N4O3
SKU: SIH-609 Categories: ,

Clear
SIH-609-10074-G5-Chemical-Structure
Product Name 10074-G5
Description

c-Myc inhibitor

Purity >98% (TLC); NMR (Conforms)
CAS No. 413611-93-5
Molecular Formula C18H12N4O3
Molecular Weight 332.3
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility May be dissolved in DMSO (40 mg/ml)
Source Synthetic
Appearance Orange powder
SMILES C1=CC=C(C=C1)C2=CC=CC=C2NC3=CC=C(C4=NON=C34)[N+](=O)[O-]
InChI InChI=1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H
InChIKey KMJPYSQOCBYMCF-UHFFFAOYSA-N
Safety Phrases Classification: Danger. Hazard Statements
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes:,
P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Cite This Product 10074-G5 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-609)

Biological Description

Alternative Names 7-Nitro-N-(2-phenylphenyl)-2,1,3-benzoxadiazol-4-amine
Research Areas Alzheimer's Disease, Amyloid, Epitope Tags, Myc Tag, Neurodegeneration, Neuroscience, Tags and Cell Markers
PubChem ID 2836600
Scientific Background 10074-G5 is a small molecule that inhibits c-Myc transcriptional activity by disrupting c-Myc/Max heterodimer formation. It also binds to monomeric amyloid-β (Aβ) peptide, inhibiting its aggregation through interference with nucleation pathways. This dual activity makes 10074-G5 a valuable tool in cancer and Alzheimer’s disease research, where c-Myc dysregulation and Aβ aggregation are key pathological features.
References 1. Follis A.V. et al. (2008) Chem. Biol. 15: 1149. 2. Heller G.T. (2020) ScienceAdvances. 6(45): DOI: 10.1126/sciadv.abb5924.

Product Images

<p>Chemical structure of 10074-G5 (SIH-609), a c-Myc inhibitor. CAS #: 413611-93-5. Molecular Formula: C18H12N4O3. Molecular Weight: 332.3 g/mol.</p>

Chemical structure of 10074-G5 (SIH-609), a c-Myc inhibitor. CAS #: 413611-93-5. Molecular Formula: C18H12N4O3. Molecular Weight: 332.3 g/mol.

Reviews

1 review for 10074-G5

  1. 5 out of 5

    :

    Based on validation through cited publications.

Add a review

Your email address will not be published. Required fields are marked *