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| Product Name | Forskolin |
| Description |
Adenylate cyclase activator |
| Purity | >99% |
| CAS No. | 66575-29-9 |
| Molecular Formula | C22H34O7 |
| Molecular Weight | 410.51 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Activator |
| Solubility | Soluble to 100 mM in DMSO, and to 10 mM in ethanol |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O |
| InChI | InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,2 |
| InChIKey | OHCQJHSOBUTRHG-KGGHGJDLSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H312 Precautionary Phrases: P280 |
| Cite This Product | Forskolin (StressMarq Biosciences, Canada, Cat # SIH-208) |
Biological Description
| Alternative Names | (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl acetate |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 47936 |
| Scientific Background | Forskolin is a diterpene that activates adenylate cyclase, leading to increased intracellular cAMP levels. In neurodegenerative disease research, forskolin is widely used to modulate synaptic plasticity, memory formation, and neuroprotection. Its role in enhancing cAMP signaling makes it a key compound in studies of learning, long-term potentiation, and neuropsychiatric disorders. |
| References |
1. Passeron T., Namiki T., Passeron H.J., Le Pape E., and Hearing V.J. (2009) J Invest Dermatol. 129(1): 162-166. 2. McEwan D.G., Brunton V.G., Baillie G.S., Leslie N.R., Houslay M.D., and Frame M.C. (2007) Cancer Research. 67(11). 3. Pescosolido N., and Librando A. (2010) Clin Ter. 161(3): e81-5. |
Product Images
Chemical structure of Forskolin (SIH-208), a Adenylate cyclase activator. CAS #: 66575-29-9. Molecular Formula: C22H34O7. Molecular Weight: 410.51 g/mol.
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