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| Product Name | Hsp70 TKD Peptide |
| Description |
Hsp70 Peptide |
| Purity | >98% |
| Molecular Formula | TKDNNLLGRFELSG |
| Molecular Weight | 1363 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Activator |
| Solubility | In aqueous solution |
| Source | Synthetic |
| Appearance | Solid |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | TKD Peptide (Hsp70 Peptide) (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-118) |
Biological Description
| Research Areas | Cancer, Heat Shock |
| Scientific Background | The Hsp70 TKD peptide is a synthetic fragment derived from the heat shock protein 70 (Hsp70), specifically the amino acid sequence TKDNNLLGRFELSG. In neurodegenerative disease research, Hsp70 and its derivatives are of interest due to their roles in protein folding, stress response, and immune modulation. The TKD peptide has been shown to activate natural killer (NK) cells and enhance immune surveillance, which may be beneficial in clearing damaged or aggregated proteins in neurodegenerative conditions. Its immunomodulatory properties suggest potential for therapeutic strategies aimed at enhancing neuroimmune interactions. |
| References |
1. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J.Mol. Evol.38(1): 1-17. 2. Rothman J. (1989), Cell 59: 591 -601. 3. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 4. Bork P., Sander C. & Valencia A. (1992) Proc. Natl Acad. Sci. USA 89:7290-7294. 5. Multhoff G., et al. (2001) Cell Stress Chaperones 6 (4): 337-344. 6. Krause, S. W. et al. (2004) Clin. Cancer Res. 10(11): 3699-3707. |
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