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| Product Name | Veratridine |
| Description |
Na channel activator |
| Purity | >98% |
| CAS No. | 71-62-5 |
| Molecular Formula | C36H51NO11 |
| Molecular Weight | 673.79 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Activator |
| Solubility | Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml) |
| Source | Synthetic |
| Appearance | White solid |
| SMILES | C[C@H]1CC[C@H]2[C@@]([C@]3([C@H](C[C@]4([C@@H]5CC[C@H]6[C@]7([C@]5(C[C@]4([C@@H]3CN2C1)O)O[C@@]6([C@H](CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O |
| InChI | InChI=1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29 |
| InChIKey | FVECELJHCSPHKY-UIHGVQCZSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302-H315-H317-H318-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338 |
| Cite This Product | Veratridine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-300) |
Biological Description
| Alternative Names | (3β,4α,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3-yl 3,4-dimethoxybenzoate |
| Research Areas | Ion Channels, Neuroscience, Sodium Channels |
| PubChem ID | 6280 |
| Scientific Background | Veratridine is a steroid-derived alkaloid that functions as a neurotoxin by persistently activating voltage-gated sodium channels. It binds to intramembrane receptor site 2, leading to prolonged sodium influx and increased intracellular calcium levels. This compound is commonly used in neuroscience to model excitotoxicity and investigate calcium-dependent signaling pathways, neuronal excitability, and neurodegenerative processes. |
| References | 1. Sperelakis N., Pappano A.J. (1969) J Gen Physiol. 53(1): 97-114. |
Product Images
Chemical structure of Veratridine (SIH-300), a Na channel opener. CAS #: 71-62-5. Molecular Formula: C36H51NO11. Molecular Weight: 673.79 g/mol.
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