Noopept

Neuroprotective Agent

Catalog No. SIH-636

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CAS No. 157115-85-0
Molecular Formula C17H22N2O4
SKU: SIH-636 Categories: ,

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SIH-636-Noopept-Chemical-Structure
Product Name Noopept
Description

Neuroprotective Agent

Purity >98% (HPLC); NMR (conforms)
CAS No. 157115-85-0
Molecular Formula C17H22N2O4
Molecular Weight 318.4
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Agent
Solubility May be dissolved in DMSO (25 mg/ml)
Source Synthetic
Appearance White powder
SMILES O=C(CC1=CC=CC=C1)N2CCC[C@H]2C(NCC(OCC)=O)=O
InChI Inchi=1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1
InChIKey PJNSMUBMSNAEEN-AWEZNQCLSA-N
Safety Phrases Not a hazardous substance or mixture.
Cite This Product Noopept (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-636)

Biological Description

Alternative Names 1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester; or N-Phenylacetyl-L-prolylglycine ethyl ester; SGS-111; GVS 111
Research Areas Glutamate Receptors, Neurodegeneration, Neuroscience, Neurotransmission, Neurotransmitter Receptors, Parkinson's Disease, Synuclein
PubChem ID 180496
Scientific Background Noopept is a synthetic dipeptide with nootropic and neuroprotective properties. It enhances cognitive function and memory, and stimulates the expression of neurotrophic factors such as NGF and BDNF in the hippocampus. Noopept protects neurons from glutamate-induced toxicity and rescues alpha-synuclein amyloid toxicity in cellular models. Its ability to modulate neurotrophic signaling and reduce oxidative stress makes it a candidate for therapeutic exploration in neurodegenerative diseases like Alzheimer's and Parkinson's.
References 1.,RU Ostrovskaya et al. J. Psychopharmacol. 2007 21:611
2.,X Jia et al. J. Mol. Biol. 2011 414:699
3.,RU Ostrovskaya et al. Bull. Exp. Biol. Med. 2008 146:334
4.,TA Antipova et al. Bull. Exp. Biol. Med. 2016 161:58
5.,RU Ostrovskaya et al. Bull. Exp. Biol. Med. 2014 156:342

Product Images

<p>Chemical structure of Adiporon (SIH-635), a Adiponectin Receptor Agonist. CAS #: 924416-43-3. Molecular Formula: C27H28N2O3. Molecular Weight: 428.5 g/mol.</p>

Chemical structure of Adiporon (SIH-635), a Adiponectin Receptor Agonist. CAS #: 924416-43-3. Molecular Formula: C27H28N2O3. Molecular Weight: 428.5 g/mol.

<p>Chemical structure of Noopept (SIH-636), a Neuroprotective. CAS #: 157115-85-0 . Molecular Formula: C17H22N2O4. Molecular Weight: 318.4 g/mol.</p>

Chemical structure of Noopept (SIH-636), a Neuroprotective. CAS #: 157115-85-0 . Molecular Formula: C17H22N2O4. Molecular Weight: 318.4 g/mol.

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