Product Name | Noopept |
Description |
Neuroprotective Agent |
Purity | >98% (HPLC); NMR (conforms) |
CAS No. | 157115-85-0 |
Molecular Formula | C17H22N2O4 |
Molecular Weight | 318.4 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Agent |
Solubility | May be dissolved in DMSO (25 mg/ml) |
Source | Synthetic |
Appearance | White powder |
SMILES | O=C(CC1=CC=CC=C1)N2CCC[C@H]2C(NCC(OCC)=O)=O |
InChI | Inchi=1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1 |
InChIKey | PJNSMUBMSNAEEN-AWEZNQCLSA-N |
Safety Phrases | Not a hazardous substance or mixture. |
Cite This Product | Noopept (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-636) |
Alternative Names | 1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester; or N-Phenylacetyl-L-prolylglycine ethyl ester; SGS-111; GVS 111 |
Research Areas | Glutamate Receptors, Neurodegeneration, Neuroscience, Neurotransmission, Neurotransmitter Receptors, Parkinson's Disease, Synuclein |
PubChem ID | 180496 |
Scientific Background | Noopept is a synthetic dipeptide with nootropic and neuroprotective properties. It enhances cognitive function and memory, and stimulates the expression of neurotrophic factors such as NGF and BDNF in the hippocampus. Noopept protects neurons from glutamate-induced toxicity and rescues alpha-synuclein amyloid toxicity in cellular models. Its ability to modulate neurotrophic signaling and reduce oxidative stress makes it a candidate for therapeutic exploration in neurodegenerative diseases like Alzheimer's and Parkinson's. |
References |
1.,RU Ostrovskaya et al. J. Psychopharmacol. 2007 21:611 2.,X Jia et al. J. Mol. Biol. 2011 414:699 3.,RU Ostrovskaya et al. Bull. Exp. Biol. Med. 2008 146:334 4.,TA Antipova et al. Bull. Exp. Biol. Med. 2016 161:58 5.,RU Ostrovskaya et al. Bull. Exp. Biol. Med. 2014 156:342 |
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