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| Product Name | Idebenone |
| Description |
Quinone antioxidant |
| Purity | >98% (TLC and HPLC); NMR (Conforms) |
| CAS No. | 58186-27-9 |
| Molecular Formula | C19H30O5 |
| Molecular Weight | 338.44 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Antioxidant |
| Solubility | Soluble to 100 mM in DMSO, 100 mM in ethanol |
| Source | Synthetic |
| Appearance | Orange Solid |
| SMILES | CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO |
| InChI | InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 |
| InChIKey | JGPMMRGNQUBGND-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | Idebenone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-150) |
Biological Description
| Alternative Names | 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone |
| Research Areas | Cancer, Oxidative Stress |
| PubChem ID | 3686 |
| Scientific Background | Idebenone is a synthetic analog of coenzyme Q10 with potent antioxidant properties. It has been investigated for multiple neurodegenerative conditions, including Alzheimer’s disease, Friedreich’s ataxia, and Duchenne muscular dystrophy. Idebenone supports mitochondrial function and reduces oxidative stress, both of which are critical in neurodegeneration. Its neuroprotective effects and ability to enhance cellular energy metabolism make it a promising therapeutic agent for disorders characterized by mitochondrial dysfunction and oxidative damage. |
| References |
1. Gutzmann H., Kuhl K.P., Hadler D and Rapp M.A. (2002) Pharmacopsychiatry. 35(1): 12-18. 2. Di Prospero N.A., Baker A., Jeffries N, Fischbeck K.H. (2007) Lancet Neuro. 6(10): 878-886. 3. McDaniel D., Neudecker B., Dinardo J, Lewis J., Maibach H. (2005) Cosmet Dermatol. 4(3): 167-173. |
Product Images
Chemical structure of Idebenone (SIH-150), a Quinone antioxidant and free radical scavenger. CAS #: 58186-27-9. Molecular Formula: C19H30O5. Molecular Weight: 338.44 g/mol.
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