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| Product Name | Muscone |
| Description |
Antiinflammatory and Neuroprotective activity |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 541-91-3 |
| Molecular Formula | C16H30O |
| Molecular Weight | 238.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Blocker |
| Solubility | May be dissolved in DMSO (35 mg/ml); or Ethanol (35 mg/ml) |
| Source | Synthetic |
| Appearance | Colorless oil |
| SMILES | CC1CCCCCCCCCCCCC(=O)C1 |
| InChI | InChI=1S/C16H30O/c1-15-12-10-8-6-4-2-3-5-7-9-11-13-16(17)14-15/h15H,2-14H2,1H3 |
| InChIKey | ALHUZKCOMYUFRB-UHFFFAOYSA-N |
| Safety Phrases | GHS Hazard Statements: Not Classified |
| Cite This Product | Muscone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-612) |
Biological Description
| Alternative Names | 3-Methyl-cyclopentadecanone (racemic) |
| Research Areas | Angiogenesis, Cardiovascular System |
| PubChem ID | 10947 |
| Scientific Background | Muscone is a macrocyclic ketone found in musk deer secretions, known for its anti-inflammatory and neuroprotective properties. In neuroscience, Muscone has shown efficacy in reducing neuronal damage and inflammation in models of cervical spondylotic myelopathy and inflammatory pain. It acts through pathways such as NOX4/JAK2-STAT3 and NLRP3 inflammasome inhibition. Additionally, Muscone has demonstrated cardioprotective effects, suggesting its potential in treating neurocardiological disorders. |
| References |
1. Ahmed L., et al. (2018) Proc. Acad. Natl. Sci. USA. 115:E3950 2. Zhou L.Y., et al. (2020) J. Neurochem. 155:154 3. Yu S., et al. (2020) Int. Immunopharmacol. 82:106355 4. Wei C.J., et al. (2021) J. Biol. Regul. Homeost. Agents. 35:85 5. Du Y., et al. (2018) Am. J. Transl. Res. 10:4235 6. Du Y., et al. (2018) Med. Sci. Monit. 24:8870 |
Product Images
Chemical structure of Muscone (SIH-612), a Antiinflammatory and Neuroprotective activity. CAS #: 541-91-3. Molecular Formula: C16H30O. Molecular Weight: 238.4 g/mol.
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