Tetrodotoxin citrate

Sodium Channel Blocker

Catalog No. SIH-603

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CAS No. 18660-81-6
Molecular Formula C11H17N3O8
SKU: SIH-603 Categories: ,

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SIH-603-Tetrodotoxin-Citrate-Chemical-Structure.png
Product Name Tetrodotoxin citrate
Description

Sodium Channel Blocker

Purity ≥98% (HPLC); NMR (Conforms)
CAS No. 18660-81-6
Molecular Formula C11H17N3O8
Molecular Weight 319.27
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Blocker
Solubility Maybe dissolved in buffer or distilled water as needed.
Source Synthetic
Appearance White powder
SMILES C(C(=O)O)C(CC(=O)O)(C(=O)O)O.C(C1(C2C3C(N=C(NC34C(C1OC(C4O)(O2)O)O)N)O)O)O
InChI InChI=1S/C11H17N3O8.C6H8O7/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-7,15-20H,1H2,(H3,12,13,14);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t2-,3-,4+,5
InChIKey YUJWMDOXROTQCW-WNGAXIQVSA-N
Safety Phrases Classification: Severe poison. H300 Fatal if swallowed
H310 Fatal in contact with skin
H330 Fatal if inhaled
Precautionary statement(s):
P260 Do not breathe dust/fume/gas/mist/vapours/spray
P262 Do not get in eyes, on skin, or on clothing
P264 Wash hands thoroughly after handling
P280 Wear protective gloves/protective clothing/eye protection/face protection
P284 Wear respiratory protection
P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
P302+350 IF ON SKIN: Gently wash with soap and water
P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
Cite This Product Tetrodotoxin citrate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-603)

Biological Description

Alternative Names TTX citrate
Research Areas Cancer, Cell Signaling, Ion Channels, Neuroscience, Sodium Channels, Voltage-Gated Sodium Channels
PubChem ID 54592378
Scientific Background Tetrodotoxin citrate is the water-soluble citrate salt form of tetrodotoxin, retaining its potent and selective inhibition of voltage-gated sodium channels. Its enhanced solubility facilitates its use in in vitro and in vivo neuroscience studies. Tetrodotoxin citrate is employed to investigate neuronal signaling, action potential propagation, and sodium channel dysfunction in neurodegenerative and neuropsychiatric disorders.

Product Images

<p>Chemical structure of Tetrodotoxin Citrate (SIH-603), a Sodium Channel Blocker. CAS #: 18660-81-6. Molecular Formula: C11N17N3O8. Molecular Weight: 319.27 g/mol.</p>

Chemical structure of Tetrodotoxin Citrate (SIH-603), a Sodium Channel Blocker. CAS #: 18660-81-6. Molecular Formula: C11N17N3O8. Molecular Weight: 319.27 g/mol.

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