Product Name | Tetrodotoxin citrate |
Description |
Sodium Channel Blocker |
Purity | ≥98% (HPLC); NMR (Conforms) |
CAS No. | 18660-81-6 |
Molecular Formula | C11H17N3O8 |
Molecular Weight | 319.27 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Blocker |
Solubility | Maybe dissolved in buffer or distilled water as needed. |
Source | Synthetic |
Appearance | White powder |
SMILES | C(C(=O)O)C(CC(=O)O)(C(=O)O)O.C(C1(C2C3C(N=C(NC34C(C1OC(C4O)(O2)O)O)N)O)O)O |
InChI | InChI=1S/C11H17N3O8.C6H8O7/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-7,15-20H,1H2,(H3,12,13,14);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t2-,3-,4+,5 |
InChIKey | YUJWMDOXROTQCW-WNGAXIQVSA-N |
Safety Phrases |
Classification: Severe poison. H300 Fatal if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled Precautionary statement(s): P260 Do not breathe dust/fume/gas/mist/vapours/spray P262 Do not get in eyes, on skin, or on clothing P264 Wash hands thoroughly after handling P280 Wear protective gloves/protective clothing/eye protection/face protection P284 Wear respiratory protection P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician P302+350 IF ON SKIN: Gently wash with soap and water P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing |
Cite This Product | Tetrodotoxin citrate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-603) |
Alternative Names | TTX citrate |
Research Areas | Cancer, Cell Signaling, Ion Channels, Neuroscience, Sodium Channels, Voltage-Gated Sodium Channels |
PubChem ID | 54592378 |
Scientific Background | Tetrodotoxin citrate is the water-soluble citrate salt form of tetrodotoxin, retaining its potent and selective inhibition of voltage-gated sodium channels. Its enhanced solubility facilitates its use in in vitro and in vivo neuroscience studies. Tetrodotoxin citrate is employed to investigate neuronal signaling, action potential propagation, and sodium channel dysfunction in neurodegenerative and neuropsychiatric disorders. |
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