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| Product Name | Lenalidomide |
| Description |
Ubiquitin ligase inducer |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 191732-72-6 |
| Molecular Formula | C13H13N3O3 |
| Molecular Weight | 259.26 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inducer |
| Solubility | Soluble in DMSO (200 mM), Water (<1 mM) and Ethanol (<1 mM). |
| Source | Synthetic |
| Appearance | Powder |
| SMILES | C1=CC=C(C3=C1C(N(C2C(NC(=O)CC2)=O)C3)=O)N |
| InChI | InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18) |
| InChIKey | GOTYRUGSSMKFNF-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Acute toxicity, Oral (Category 4), Acute toxicity, Dermal (Category 4), Acute toxicity, Inhalation (Category 4), Reproductive toxicity (Category 1B) Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H301- Harmful if swallowed. H312- Harmful in contact with skin. H332- Harmful if inhaled. H360-May damage fertility or the unborn child. Precautionary statements: P261- Avoid breathing dust/fumes/gas/mist/vapors/spray. P263- Avoid contact during pregnancy/while nursing. P270- Do not eat, drink or smoke when using this product. P280- Wear protective gloves/protective clothing. P301+P310- IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352- IF ON SKIN: Wash with plenty of soap and water. P304+P340- IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P308+P313- IF exposed or concerned: Get medical advice/attention. P330- Rinse mouth. P405- Store locked up. P501- Dispose of contents/container to a licensed disposal company. |
| Cite This Product | Lenalidomide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-410) |
Biological Description
| Alternative Names | 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione |
| Research Areas | Cell Signaling, Post-translational Modifications |
| PubChem ID | 216326 |
| Scientific Background | Lenalidomide is an immunomodulatory and anti-inflammatory agent known for its ability to modulate cytokine production and enhance T-cell and natural killer cell activity. In neuroscience, lenalidomide is investigated for its neuroprotective effects in models of neurodegeneration and brain injury. It reduces neuroinflammation and promotes neuronal survival, making it a candidate for therapeutic intervention in diseases such as Alzheimer's and Parkinson's. Lenalidomide’s influence on immune signaling and neurotrophic factors contributes to its potential in modulating neurodegenerative processes and improving cognitive outcomes. |
| References |
1. Krönke J., et al. (2014) Science. 343(6168): 301-5. 2. Lu G., et al. (2014) Science. 343(6168): 305-9. |
Product Images
Chemical structure of Lenalidomide (SIH-410), a Ubiquitin ligase inducer. CAS #: 191732-72-6 . Molecular Formula: C13H13N3O3. Molecular Weight: 259.26 g/mol.
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