AP-18

Name: AP-18
SKU: SIH-310
Availability: InStock

TRPA1 blocker

Catalog No. SIH-310

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CAS No.	55224-94-7
Molecular Formula	C11H12ClNO

SKU: SIH-310 Categories: Inhibitor, Small Molecules

Product Name	AP-18
Description	TRPA1 blocker
Purity	>98%
CAS No.	55224-94-7
Molecular Formula	C₁₁H₁₂ClNO
Molecular Weight	209.67
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble to 100 mM in DMSO and to 100 mM in ethanol
Source	Synthetic
Appearance	White Solid
SMILES	C/C(=CC1=CC=C(C=C1)Cl)/C(=N/O)/C
InChI	InChI=1S/C11H12ClNO/c1-8(9(2)13-14)7-10-3-5-11(12)6-4-10/h3-7,14H,1-2H3/b8-7-,13-9+
InChIKey	MHTJEUOFLVQMCL-XTYDYKDCSA-N
Safety Phrases	Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
Cite This Product	AP-18 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-310)

Alternative Names	(2E,3E)-4-(4-Chlorophenyl)-N-hydroxy-3-methyl-3-buten-2-imine
Research Areas	Ion Channels, Neuroscience
PubChem ID	16725814
Scientific Background	AP-18 is a reversible TRPA1 channel blocker. They exhibit fibroblast-like morphology, slow growth and contact inhibition (1).
References	1. Doi H., et al. (2005) Tohoku J Exp Med. 207(3): 209-216.

Chemical structure of AP-18 (SIH-310), a TRPA1 blocker. CAS #: 55224-94-7. Molecular Formula: C11H12ClNO. Molecular Weight: 209.67 g/mol.

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