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| Product Name | BCTC |
| Description |
TRPV1 blocker |
| Purity | >98% |
| CAS No. | 393514-24-4 |
| Molecular Formula | C20H25ClN4O |
| Molecular Weight | 372.89 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 100 mM in DMSO and to 40 mM in ethanol |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl |
| InChI | InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26) |
| InChIKey | ROGUAPYLUCHQGK-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | BCTC (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-307) |
Biological Description
| Alternative Names | 4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide |
| Research Areas | Ion Channels, Neuroscience |
| PubChem ID | 9929425 |
| Scientific Background | BCTC is an inhibitor of capsaicin- and acid-mediated currents at the TRPV1 receptor, also known as the vanilloid receptor 1. It has demonstrated efficacy in models of acute, inflammatory, and neuropathic pain. In neuroscience, BCTC is used to investigate TRPV1's role in nociception, thermoregulation, and neuroinflammatory processes associated with chronic pain and neurodegeneration. |
| References |
1. Pomonis J.D., et al. (2003) J Pharmacol Exp Ther. 306(1): 387-393. 2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386. |
Product Images
Chemical structure of BCTC (SIH-307), a TRPV1 blocker. CAS #: 393514-24-4. Molecular Formula: C20H25ClN4O. Molecular Weight: 372.89 g/mol.
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