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| Product Name | BML-210 |
| Description |
HDAC inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 537034-17-6 |
| Molecular Formula | C20H25N3O2 |
| Molecular Weight | 339.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol |
| Source | Synthetic |
| Appearance | Tan Solid |
| SMILES | C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NC2=CC=CC=C2N |
| InChI | InChI=1S/C20H25N3O2/c21-17-12-8-9-13-18(17)23-20(25)15-7-2-1-6-14-19(24)22-16-10-4-3-5-11-16/h3-5,8-13H,1-2,6-7,14-15,21H2,(H,22,24)(H,23,25) |
| InChIKey | RFLHBLWLFUFFDZ-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution- Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes Hazard Statements: H413 – May cause long lasting harmful effects to aquatic life. |
| Cite This Product | Bml-210 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-348) |
Biological Description
| Alternative Names | N1-(2-aminophenyl)-N8-phenyloctanediamide |
| Research Areas | Cancer, Cell Signaling |
| PubChem ID | 9543540 |
| Scientific Background | A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines. |
| References |
1. Savickiene J., et al. (2006) Eur. J. Pharmacol. 549: 9. 2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551. |
Product Images
Chemical structure of BML-210 (SIH-348), a HDAC inhibitor. CAS #: 537034-17-6. Molecular Formula: C20H25N3O2 . Molecular Weight: 339.4 g/mol.
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