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| Product Name | Clozapine N-oxide |
| Description |
Activator of DREADDs |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 34233-69-7 |
| Molecular Formula | C18H19ClN4O |
| Molecular Weight | 342.8 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Activator |
| Solubility | May be dissolved in DMSO (15 mg/ml); or ethanol (3 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow powder |
| SMILES | ClC(C=C3)=CC1=C3NC(C=CC=C2)=C2C(N4CC[N+](C)([O-])CC4)=N1 |
| InChI | InChI=1S/C18H19ClN4O/c1-23(24)10-8-22(9-11-23)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 |
| InChIKey | WYRDWWAASBTJLM-UHFFFAOYSA-N |
| Safety Phrases | GHS Classification: GHS06 Acute toxicity (oral, dermal, inhalation), categories 1,2,3 Hazard statement(s): H301-H336 |
| Cite This Product | Clozapine N-oxide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-570) |
Biological Description
| Alternative Names | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Research Areas | Cell Signaling, G Protein Signaling, GPCR, Neuroscience, Neurotransmission |
| PubChem ID | 2819 |
| Scientific Background | Clozapine N-Oxide is an agonist at human muscarinic designer receptors known as DREADDs. |
Product Images
Chemical structure of Clozapine N-Oxide (SIH-570), a Activator of DREADDs. CAS #: 34233-69-7. Molecular Formula: C18H19ClN4O. Molecular Weight: 342.8 g/mol.
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