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| Product Name | Duloxetine Hydrochloride |
| Description |
5-HT-noradrenaline reuptake inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 136434-34-9 |
| Molecular Formula | C18H19NOS.HCl |
| Molecular Weight | 333.9 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Blue Ice or 4ºC |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (30 mg/ml); or water (3 mg/ml) |
| Source | Synthetic |
| Appearance | White powder |
| SMILES | CNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl |
| InChI | InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1 |
| InChIKey | BFFSMCNJSOPUAY-LMOVPXPDSA-N |
| Safety Phrases |
WHMIS Classification: Not WHMIS controlled. GHS Classification: Acute toxicity, Oral (Category 4) Signal word: Warning Hazard statement(s): H302 Harmful if swallowed. Precautionary statement(s) none HMIS Classification: Health hazard: 1 Flammability: 0 Physical hazards: 0 Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Skin - Harmful if absorbed through skin. May cause skin irritation. Eyes - May cause eye irritation. Ingestion - Harmful if swallowed. |
| Cite This Product | Duloxetine HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-549) |
Biological Description
| Alternative Names | Duloxetine Hydrochloride, (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride, (S)-Duloxetine hydrochloride, (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride, (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride, (+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride, (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride, Duloxetine HCl |
| Research Areas | Alpha-2 Adrenergic Receptors, Neuroscience, Neurotransmitter Receptors |
| PubChem ID | 60834 |
| Scientific Background | Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) widely used in the treatment of depression and neuropathic pain. In neurodegenerative disease research, Duloxetine has been investigated for its ability to modulate neuroinflammation, enhance neuroplasticity, and protect against neuronal loss. Its dual-action mechanism on monoaminergic pathways supports its use in managing cognitive and emotional symptoms associated with neurodegenerative disorders. |
Product Images
Chemical structure of Duloxetine HCl (SIH-549), a 5-HT-noradrenaline reuptake inhibitor. CAS #: 136434-34-9. Molecular Formula: C18H19NOS.HCl. Molecular Weight: 333.9 g/mol.
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