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| Product Name | SGI-1027 |
| Description |
DNA Methyl transferase inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 1020149-73-8 |
| Molecular Formula | C27H23N7O |
| Molecular Weight | 461.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (35 mg/ml) |
| Source | Synthetic |
| Appearance | Off-white powder |
| SMILES | CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54 |
| InChI | InChI=1S/C27H23N7O/c1-17-16-25(34-27(28)30-17)32-20-10-12-21(13-11-20)33-26(35)18-6-8-19(9-7-18)31-24-14-15-29-23-5-3-2-4-22(23)24/h2-16H,1H3,(H,29,31)(H,33,35)(H3,28,30,32,34) |
| InChIKey | QSYLKMKIVWJAAK-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | SGI-1027 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-596) |
Biological Description
| Alternative Names | N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide |
| Research Areas | Apoptosis, Cancer, Cell Signaling, Organelle Markers, Post-translational Modifications |
| PubChem ID | 24858111 |
| Scientific Background | SGI 1027 is a DNA methyltransferase inhibitor. It inhibits the mammalian DNA methyltransferases DNMT3B, DNMT3A and DNMT1. |
Product Images
Chemical structure of SGI-1027 (SIH-596), a DNA Methyl transferase inhibitor. CAS #: 1020149-73-8. Molecular Formula: C27H23N7O. Molecular Weight: 461.5 g/mol.
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