Proteins

  • Alpha Synuclein Pre-formed Fibrils

    Human Recombinant Alpha Synuclein PFFs (Type 2)

    Catalog No. SPR-317

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    Expression System E. coli
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    SPR-317_Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-4.png
    TEM of Type 2 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-317)Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.SDS-Page of Type 2 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-317)Type 2 alpha synuclein Pre-formed fibrils (SPR-317) do not seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) at the same rate as Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by lower fluorescence intensity values of Thioflavin T over time.Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)LDH assay shows effect of alpha synuclein PFFs on mouse primary neuronsMTT assay effects of alpha synuclein PFFs on mouse primary neurons

  • Alpha Synuclein Pre-formed Fibrils

    Human Recombinant Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-322

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    Expression System E. coli
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    SPR-322_Alpha-Synuclein-Protein-Preformed-Fibrils-Protein-TEM-7.png
    Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.ICC/IF of human Alpha Synuclein Protein Preformed Fibrils Protein (SPR-322)ICC/IF of human Alpha Synuclein Protein Preformed Fibrils Protein (SPR-322)StressMarq’s Alpha Synuclein PFFs (red) cat#SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days.SDS-Page of Type 1 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-322)Type 1 alpha synuclein Pre-formed fibrils (SPR-322) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) as shown by increased fluorescence intensity by Thioflavin T over time.Immunocytochemistry/Immunofluorescence of Human Alpha Synuclein Protein Protein (SPR-322)Mouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFsMouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFs cause endogenous alpha synuclein phosphorylationTEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-322)IHC of Sprague-Dawley rat brain injected with Type 1 human alpha synuclein Pre-formed fibrils (SPR-322)Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).

  • CDC37 Protein (Discontinued)

    Human Recombinant CDC37 Protein

    Catalog No. SPR-304

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    SPR-304_CDC37_Protein_Western Blot.png

  • Cpn10 Protein (Discontinued)

    Human Recombinant Cpn10 Protein

    Catalog No. SPR-310

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    SPR-310_Cpn10_Protein_SDS-Page.png

  • MOLECULAR SIGNATURE® Crotonaldehyde BSA Conjugate

    Bovine Serum Albumin (BSA) modified with Crotonaldehyde

    Catalog No. SPR-207

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    Expression System Synthetic
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    SPR-207_Crotonaldehyde-BSA-Conjugate-Protein-Western-Blot-1.png

  • MOLECULAR SIGNATURE® Galactose BSA Glycoconjugate (Discontinued)

    Glycated Bovine Serum Albumin (BSA) with β-Galactose

    Catalog No. SPR-203

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    SPR-203_Galactose-BSA-Glycoconjugate-Protein-Western-Blot-1.png

  • MOLECULAR SIGNATURE® Glucose BSA Glycoconjugate (Discontinued)

    Glycated Bovine Serum Albumin (BSA) with β-Glucose

    Catalog No. SPR-204

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    SPR-204_Glucose-BSA-Glycoconjugate-Protein-Western-Blot-1.png

  • GRP78 (Bip) Protein

    Human Recombinant GRP78 (Bip) Protein

    Catalog No. SPR-107

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    SPR-107_GRP78_Protein_SDS-Page.png

  • GRP78 (Bip) Protein

    Human Recombinant GRP78 (Bip) Full Length Protein

    Catalog No. SPR-119

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    SPR-119_GRP78_Protein_SDS-Page.png

  • MOLECULAR SIGNATURE® Hexanoyl-Lysine adduct BSA Conjugate

    Bovine Serum Albumin (BSA) modified with Hexanoyl-Lysine adduct (HEL)

    Catalog No. SPR-205

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    SPR-205_Hexanoyl-Lysine-adduct-BSA-Conjugate-Protein-Western-Blot-1.png

  • HO-1 Protein (Discontinued)

    Rat Recombinant HO-1 Partial Protein

    Catalog No. SPR-315

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    SPR-315_HO-1-Protein-SDS-Page-1.png

  • HOP Protein

    Human Recombinant HOP Protein

    Catalog No. SPR-302

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    SPR-302_HOP_Protein_SDS-Page.png

  • HSC70 Protein

    Human Recombinant HSC70 Protein

    Catalog No. SPR-106

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    SPR-106_HSC70_Protein_SDS-Page.png

  • HSP27 Protein (Discontinued)

    Human Recombinant HSP27 Full Length Protein

    Catalog No. SPR-118

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  • HSP60 Protein

    Human Recombinant HSP60 Protein

    Catalog No. SPR-104

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    SPR-104_HSP60_Protein_SDS-Page.png

  • HSP65 Protein

    Mycobacterium bovis BCG Recombinant HSP65 Protein

    Catalog No. SPR-116

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    SPR-116_HSP65_Protein_SDS-Page.png