Products

  • MOLECULAR SIGNATURE® Hexanoyl-Lysine adduct BSA Conjugate

    Bovine Serum Albumin (BSA) modified with Hexanoyl-Lysine adduct (HEL)

    Catalog No. SPR-205

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    Expression System Synthetic
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    SPR-205_Hexanoyl-Lysine-adduct-BSA-Conjugate-Protein-Western-Blot-1.png

  • MOLECULAR SIGNATURE® 4-Hydroxy-2-hexenal BSA Conjugate

    Bovine Serum Albumin (BSA) modified with 4-Hydroxy-2-hexenal (4-HHE)

    Catalog No. SPR-210

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    Expression System Synthetic
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    SPR-210_4-Hydroxy-2-hexenal-BSA-Conjugate-Protein-Western-Blot-1.png

  • MOLECULAR SIGNATURE® Acrolein BSA Conjugate

    Bovine Serum Albumin (BSA) modified with Acrolein

    Catalog No. SPR-206

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    Expression System Synthetic
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    SPR-206_Acrolein-BSA-Conjugate-Protein-Western-Blot-1.png

  • MOLECULAR SIGNATURE® Malondialdehyde BSA Conjugate

    Bovine Serum Albumin (BSA) modified with Malondialdehyde

    Catalog No. SPR-209

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    Expression System Synthetic
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    SPR-209_Malondialdehyde-BSA-Conjugate-Protein-Western-Blot-1.png

  • Alpha Synuclein Monomers

    Human Recombinant Alpha Synuclein Monomers (Type 2)

    Catalog No. SPR-316

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    Expression System E. coli
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    SPR-316_Alpha-Synuclein-Protein-Monomer-Protein-SDS-Page-1.png
    Alpha Synuclein monomers (SPR-316) do not form new alpha synuclein fibrils when combined with Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by a limited increase in fluorescence intensity by Thioflavin T over time.Alpha Synuclein Monomer RT-QuiC AssayΑlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.LDH assay shows effect of alpha synuclein monomers on mouse primary neuronsMTT assay shows effects of alpha synuclein monomers on mouse primary neurons

  • p23 Protein

    Human Recombinant p23 Protein

    Catalog No. SPR-303

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    Expression System E. coli
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    SPR-303_p23-Protein-SDS-Page-1.png

  • HOP Protein

    Human Recombinant HOP Protein

    Catalog No. SPR-302

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    Expression System E. coli
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    SPR-302_HOP_Protein_SDS-Page.png

  • AHA1 Protein

    Human Recombinant AHA1 Protein

    Catalog No. SPR-300

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    Expression System E. coli
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    SPR-300_AHA1_Protein_SDS-Page.png

  • Tau-441 (2N4R) P301S Mutant Monomers

    Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers

    Catalog No. SPR-327

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    Expression System E. coli
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    SPR-327_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in active tau monomers (SPR-327). A greater increase in fluorescence is seen when 50 μM active monomer (SPR-327) is combined with 10 μM of active fibrils (SPR-329 or SPR-330), as the active fibrils seed the formation of new fibrils from the pool of active monomers.

  • Alpha Synuclein A53T Mutant Monomers

    Human Recombinant Alpha Synuclein A53T Mutant Monomers (Type 1)

    Catalog No. SPR-325

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    Expression System E. coli
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    SPR-325_A53T-Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.Cisbio Total Alpha Synuclein AssayCisbio Alpha Synuclein Aggregation Assay