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| Product Name | Phenylacetyl-L-glutamine |
| Description |
Bioactive gut microbial metabolite |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 28047-15-6 |
| Molecular Formula | C13H16N2O4 |
| Molecular Weight | 264.3 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inducer |
| Solubility | May be dissolved in DMSO (45 mg / ml) |
| Source | Synthetic |
| Appearance | Off-white powder |
| SMILES | C1=CC=C(C=C1)CC(=O)NC(CCC(=O)N)C(=O)O |
| InChI | InChI=1S/C13H16N2O4/c14-11(16)7-6-10(13(18)19)15-12(17)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,14,16)(H,15,17)(H,18,19)/t10-/m0/s1 |
| InChIKey | JFLIEFSWGNOPJJ-JTQLQIEISA-N |
| Safety Phrases |
Classification: Warning Hazard Statements, H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Precautionary Statement Codes,: P264, P270, P301+P317, P330, and P501 |
| Cite This Product | Phenylacetyl-L-glutamine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-611) |
Biological Description
| Alternative Names | (S)-5-Amino-5-oxo-2-(2-phenylacetamido)pentanoic acid; N-Phenylacetylglutamine; Phenylacetylglutamine; Phenyl-Ac-Gln-OH; NSC-203800; PAG |
| Research Areas | Cardiovascular System |
| PubChem ID | 92258 |
| Scientific Background | Phenylacetyl-L-glutamine (PAG) is a gut microbiota-derived metabolite frequently studied in metabolomics and cardiovascular research. While its direct role in neurodegenerative disease is limited, PAG's interaction with adrenergic receptors and its systemic effects on inflammation and vascular health may have indirect implications for brain aging and neurovascular integrity. Its presence in plasma is being explored as a biomarker for disease risk, making it a valuable compound in systems biology and precision medicine. |
| References |
1.Romano K.A., et al. (2022) Circ. Heart. Fail. e009972 Online ahead of print 2.Nemet I., et al. (2020) Cell. 180:862 3.Yua F., et al. (2022) Front. Cardiovasc. Med. 9:944155 |
Product Images
Chemical structure of Phenylacetyl-L-glutamine (SIH-611), a Bioactive gut microbial metabolite. CAS #: 28047-15-6. Molecular Formula: C13H16N2O4. Molecular Weight: 264.3 g/mol.
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