Parkinson's Disease

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  • Alpha Synuclein A53T Mutant Monomers

    Human Recombinant Alpha Synuclein A53T Mutant Monomers (Type 1)

    Catalog No. SPR-325

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    Expression System E. coli
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    SPR-325_A53T-Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.Cisbio Total Alpha Synuclein AssayCisbio Alpha Synuclein Aggregation Assay

  • Alpha Synuclein A53T Mutant Pre-formed Fibrils

    Human Recombinant Alpha Synuclein A53T Mutant PFFs (Type 1)

    Catalog No. SPR-326

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    Expression System E. coli
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    SPR-326_A53T-Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-2.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.ICC/IF of human A53T Alpha Synuclein Preformed Fibrils Protein (SPR-326)ICC/IF of human A53T Alpha Synuclein Preformed Fibrils Protein (SPR-326)ICC of primary rat neurons treated with A53T alpha synuclein PFFs show Lewy body inclusion formation.Cisbio Alpha Synuclein Aggregation AssayCisbio Total Alpha Synuclein AssayLDH assay shows effect of A53T alpha synuclein PFFs on mouse primary neuronsMTT assay effects of A53T alpha synuclein PFFs on mouse primary neuronsTEM of A53T alpha synuclein pre-formed fibrils (SPR-326).

  • Alpha Synuclein A90C Mutant Monomers

    Human Recombinant Alpha Synuclein A90C Mutant Monomers

    Catalog No. SPR-478

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    Expression System E. coli
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    SPR-478_Alpha-Synuclein-A90C-Mutant-Monomers-Protein-FRET-1.png
    Coomassie stain of Alpha Synuclein A90C Monomers (SPR-478)Fibril formation of Alpha Synuclein A90C Monomers (SPR-478)AFM of Alpha Synuclein A90C Monomers (SPR-478)Seeding Activity of Alpha Synuclein A90C Monomers (SPR-478)

  • Anti-Alpha Synuclein Antibody [3C11]

    Mouse Anti-Human Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-530

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    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-530 Categories: ,

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    SMC-530_Alpha-Synuclein_Antibody_3C11_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [3C11] used in Immunohistochemistry (IHC) on Rat cerebellum (SMC-530)Mouse Anti-Alpha Synuclein Antibody [3C11] used in Western Blot (WB) on Human Brain (SMC-530)Mouse Anti-Alpha Synuclein Antibody [3C11] used in Western Blot (WB) on Mouse, Rat Brain (SMC-530)Mouse Anti-Alpha Synuclein Antibody [3C11] used in Western Blot (WB) on Human Truncated Alpha Synuclein Protein (SMC-530)

  • Anti-Alpha Synuclein Antibody [10H7]

    Mouse Anti-Mouse Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-531

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    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-531 Categories: ,

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    SMC-531_Alpha-Synuclein_Antibody_10H7_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [10H7] used in Western Blot (WB) on Human, Mouse, Rat Brain (SMC-531)

  • Anti-Alpha Synuclein Antibody [3F8]

    Mouse Anti-Mouse Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-532

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    Species Reactivity Hu, Ms, Rt
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    SMC-532_Alpha-Synuclein_Antibody_3F8_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [3F8] used in Western Blot (WB) on Human, Mouse, Rat Brain (SMC-532)Mouse Anti-Alpha Synuclein Antibody [3F8] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Rat Primary hippocampal neurons treated to induce fibrils (SMC-532)

  • Anti-Alpha Synuclein Antibody [4F1]

    Mouse Anti-Mouse Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-533

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    Species Reactivity Hu, Ms, Rt
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    SMC-533_Alpha-Synuclein_Antibody_4F1_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [4F1] used in Western Blot (WB) on Human, Mouse, Rat Brain (SMC-533)Mouse Anti-Alpha Synuclein Antibody [4F1] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Rat Primary hippocampal neurons treated to induce fibrils (SMC-533)

  • Anti-Alpha Synuclein Antibody

    Rabbit Anti-Human Alpha Synuclein Polyclonal

    Catalog No. SPC-800

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    Species Reactivity Hu, Ms, Rt
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    SKU: SPC-800 Categories: ,

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    SPC-800_Alpha-Synuclein_Antibody_IHC_Human_Cerebellum_1.png
    Rabbit Anti-Alpha Synuclein Antibody used in Western blot (WB) on Brain (SPC-800)Rabbit Anti-Alpha Synuclein Antibody used in Western blot (WB) on Recombinant Protein (SPC-800)Rabbit Anti-Alpha Synuclein Antibody used in Western blot (WB) on Truncated Alpha Synuclein Protein (SPC-800)

  • Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11]

    Mouse Anti-Mouse Alpha Synuclein Aggregate Antibody Monoclonal IgG1

    Catalog No. SMC-617

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    Species Reactivity Hu, Ms
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    SKU: SMC-617 Categories: ,

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    SMC-617_Alpha-Synuclein-Aggregate-Specific_Antibody_2F11_Immuno-Gold-Labelling_1.png
    Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Binding Analysis () on (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on iPSC (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human SH-SY5Y (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Immunohistochemistry (IHC) on Mouse gut (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Western Blot (WB) on Mouse brain lysate (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Western Blot (WB) on Human HeLa (SMC-617)

  • RECOMBINANT Anti-Alpha Synuclein Antibody (pSer129) [J18]

    Rabbit Anti-Human Alpha Synuclein (pSer129) Monoclonal IgG

    Catalog No. SMC-600

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    Species Reactivity Hu, Ms
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    SKU: SMC-600 Categories: ,

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    SMC-600_Alpha-Synuclein-pSer129_Antibody_J18_IHC_Mouse_Brain_1.png
    Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human iPSC-derived neurons (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Immunohistochemistry (IHC) on Mouse Brain (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human iPSC-derived neurons (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Dot Blot (DB) on alpha synuclein peptide (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Western Blot (WB) on Human Alpha Synuclein (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Western Blot (WB) on Mouse Brain (SMC-600)

  • Anti-Alpha Synuclein Antibody (pSer129)

    Rabbit Anti-Human Alpha Synuclein pSer129 Polyclonal

    Catalog No. SPC-742

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    Species Reactivity Hu, Ms, Rt
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    SPC-742_Alpha-Synuclein-pSer129_Antibody_IHC_Mouse_Free-floating-brain-sections_63X_2.png
    ICC of alpha synuclein phospho serine 129 antibody in primary mouse neurons treated with mouse alpha synuclein PFFsRabbit Anti-Alpha Synuclein Antibody (pSer129) used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Primary hippocampal neurons treated with active Alpha Synuclein Protein Aggregate (SPR-322) at 4 µg/ml to induce fibrils (SPC-742)Rabbit Anti-Alpha Synuclein Antibody (pSer129) used in Immunohistochemistry (IHC) on Brain (SPC-742)Rabbit Anti-Alpha Synuclein Antibody (pSer129) used in Western blot (WB) on brain lysate (SPC-742)

  • Alpha Synuclein E114C Mutant Monomers: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant Monomers: ATTO 488

    Catalog No. SPR-517-A488

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    Expression System E. coli
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    SPR-517-A488_Alpha-Synuclein-E114C-Mutant-Monomers-ATTO-488-Protein-SDS-Page-1.png
    Fibril formation of ATTO-488 conjugated alpha-synuclein E114C monomers. (SPR-517-A88)

  • Alpha Synuclein E114C Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant PFFs: ATTO 488

    Catalog No. SPR-518-A488

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    Expression System E. coli
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    SPR-518-A488_Alpha-Synuclein-E114C-Mutant-Pre-formed-Fibrils-ATTO-488-Protein-ICC-IF-neuronal-uptake-1.png
    Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Fluorescent signal of alpha-synuclein E114C-ATTO-488 PFFs (SPR-518-A88)In vitro seeding activity of human Alpha Synuclein wildtype monomer in ThT assay. (SPR-518-A88)Sedimentation assay on ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils. (SPR-518-A88)SDS-PAGE analysis of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)

  • Alpha Synuclein Filaments

    Human Recombinant Alpha Synuclein Filaments

    Catalog No. SPR-450

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    Expression System E. coli
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    SKU: SPR-450 Category:

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    SPR-450_Alpha-Synuclein-Protein-Filaments-Protein-TEM-2.png
    TEM of Active Human Recombinant Alpha Synuclein Protein Filaments (SPR-450)

  • Alpha Synuclein Monomers

    Mouse Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein Monomers

    Rat Recombinant Alpha Synuclein Monomers

    Catalog No. SPR-481

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    Expression System E. coli
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    SPR-481_Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T Fluorescence Activity for Rat Alpha Synuclein Protein (SPR-481)