Parkinson's Disease

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  • Alpha Synuclein A53T Mutant Monomers

    Human Recombinant Alpha Synuclein A53T Mutant Monomers (Type 1)

    Catalog No. SPR-325

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    Expression System E. coli
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    SPR-325_A53T-Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.Cisbio Total Alpha Synuclein AssayCisbio Alpha Synuclein Aggregation Assay

  • Alpha Synuclein A53T Mutant Pre-formed Fibrils

    Human Recombinant Alpha Synuclein A53T Mutant PFFs (Type 1)

    Catalog No. SPR-326

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    Expression System E. coli
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    SPR-326_A53T-Alpha-Synuclein-Preformed-Fibrils-Protein-ICC-IF-1.png
    TEM of A53T alpha synuclein Pre-formed fibrils (SPR-326).TEM of A53T alpha synuclein Pre-formed fibrils (SPR-326)Cisbio Alpha Synuclein Aggregation AssayCisbio Total Alpha Synuclein AssayThioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.LDH assay shows effect of A53T alpha synuclein PFFs on mouse primary neuronsMTT assay effects of A53T alpha synuclein PFFs on mouse primary neurons

  • Alpha Synuclein A90C Mutant Monomers

    Human Recombinant Alpha Synuclein A90C Mutant Monomers

    Catalog No. SPR-478

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    Expression System E. coli
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    SPR-478_Alpha-Synuclein-A90C-Mutant-Monomers-Protein-FRET-1.png
    Coomassie stain of Alpha Synuclein A90C Monomers (SPR-478)Fibril formation of Alpha Synuclein A90C Monomers (SPR-478)AFM of Alpha Synuclein A90C Monomers (SPR-478)Seeding Activity of Alpha Synuclein A90C Monomers (SPR-478)

  • Anti-Alpha Synuclein Antibody [3C11]

    Mouse Anti-Human Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-530

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    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-530 Categories: ,

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    SMC-530_Alpha-Synuclein_Antibody_3C11_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [3C11] used in Immunohistochemistry (IHC) on Rat cerebellum (SMC-530)Mouse Anti-Alpha Synuclein Antibody [3C11] used in Western Blot (WB) on Human Brain (SMC-530)Mouse Anti-Alpha Synuclein Antibody [3C11] used in Western Blot (WB) on Mouse, Rat Brain (SMC-530)Mouse Anti-Alpha Synuclein Antibody [3C11] used in Western Blot (WB) on Human Truncated Alpha Synuclein Protein (SMC-530)

  • Anti-Alpha Synuclein Antibody [10H7]

    Mouse Anti-Mouse Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-531

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    Species Reactivity Hu, Ms, Rt
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    SMC-531_Alpha-Synuclein_Antibody_10H7_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [10H7] used in Western Blot (WB) on Human, Mouse, Rat Brain (SMC-531)

  • Anti-Alpha Synuclein Antibody [3F8]

    Mouse Anti-Mouse Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-532

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    Species Reactivity Hu, Ms, Rt
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    SMC-532_Alpha-Synuclein_Antibody_3F8_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [3F8] used in Western Blot (WB) on Human, Mouse, Rat Brain (SMC-532)Mouse Anti-Alpha Synuclein Antibody [3F8] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Rat Primary hippocampal neurons treated to induce fibrils (SMC-532)

  • Anti-Alpha Synuclein Antibody [4F1]

    Mouse Anti-Mouse Alpha Synuclein Monoclonal IgG1

    Catalog No. SMC-533

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    Species Reactivity Hu, Ms, Rt
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    SKU: SMC-533 Categories: ,

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    SMC-533_Alpha-Synuclein_Antibody_4F1_ICC-IF_Human_Neuroblastoma-cell-line-SK-N-BE_60X_Composite_1.png
    Mouse Anti-Alpha Synuclein Antibody [4F1] used in Western Blot (WB) on Human, Mouse, Rat Brain (SMC-533)Mouse Anti-Alpha Synuclein Antibody [4F1] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Rat Primary hippocampal neurons treated to induce fibrils (SMC-533)

  • Anti-Alpha Synuclein Antibody

    Rabbit Anti-Human Alpha Synuclein Polyclonal

    Catalog No. SPC-800

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    Species Reactivity Hu, Ms, Rt
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    SKU: SPC-800 Categories: ,

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    SPC-800_Alpha-Synuclein_Antibody_IHC_Human_Cerebellum_1.png
    Rabbit Anti-Alpha Synuclein Antibody used in Western blot (WB) on Brain (SPC-800)Rabbit Anti-Alpha Synuclein Antibody used in Western blot (WB) on Recombinant Protein (SPC-800)Rabbit Anti-Alpha Synuclein Antibody used in Western blot (WB) on Truncated Alpha Synuclein Protein (SPC-800)

  • Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11]

    Mouse Anti-Mouse Alpha Synuclein Aggregate Antibody Monoclonal IgG1

    Catalog No. SMC-617

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    Species Reactivity Hu, Ms
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    SKU: SMC-617 Categories: ,

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    SMC-617_Alpha-Synuclein-Aggregate-Specific_Antibody_2F11_Immuno-Gold-Labelling_1.png
    Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Binding Analysis () on (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on iPSC (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human SH-SY5Y (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Immunohistochemistry (IHC) on Mouse gut (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Western Blot (WB) on Mouse brain lysate (SMC-617)Mouse Anti-Alpha Synuclein Antibody (Aggregate-Specific) [2F11] used in Western Blot (WB) on Human HeLa (SMC-617)

  • Anti-Alpha Synuclein Antibody (pSer129) [J18]

    Rabbit Anti-Human Alpha Synuclein pSer129 Monoclonal IgG

    Catalog No. SMC-600

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    Species Reactivity Hu, Ms
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    SKU: SMC-600 Categories: ,

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    SMC-600_Alpha-Synuclein-pSer129_Antibody_J18_IHC_Mouse_Brain_1.png
    Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human iPSC-derived neurons (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Immunohistochemistry (IHC) on Mouse Brain (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human iPSC-derived neurons (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Dot Blot (DB) on alpha synuclein peptide (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Western Blot (WB) on Human Alpha Synuclein (SMC-600)Rabbit Anti-Alpha Synuclein Antibody (pSer129) [J18] used in Western Blot (WB) on Mouse Brain (SMC-600)

  • Anti-Alpha Synuclein Antibody (pSer129)

    Rabbit Anti-Human Alpha Synuclein pSer129 Polyclonal

    Catalog No. SPC-742

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    Species Reactivity Hu, Ms, Rt
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    SKU: SPC-742 Categories: ,

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    SPC-742_Alpha-Synuclein-pSer129_Antibody_IHC_Mouse_Free-floating-brain-sections_63X_2.png
    ICC of alpha synuclein phospho serine 129 antibody in primary mouse neurons treated with mouse alpha synuclein PFFsRabbit Anti-Alpha Synuclein Antibody (pSer129) used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Primary hippocampal neurons treated with active Alpha Synuclein Protein Aggregate (SPR-322) at 4 µg/ml to induce fibrils (SPC-742)Rabbit Anti-Alpha Synuclein Antibody (pSer129) used in Immunohistochemistry (IHC) on Brain (SPC-742)Rabbit Anti-Alpha Synuclein Antibody (pSer129) used in Western blot (WB) on brain lysate (SPC-742)

  • Alpha Synuclein E114C Mutant Monomers: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant Monomers: ATTO 488

    Catalog No. SPR-517-A488

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    Expression System E. coli
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    SPR-517-A488_Alpha-Synuclein-E114C-Mutant-Monomers-ATTO-488-Protein-SDS-Page-1.png
    Fibril formation of ATTO-488 conjugated alpha-synuclein E114C monomers. (SPR-517-A88)

  • Alpha Synuclein E114C Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Alpha Synuclein E114C Mutant PFFs: ATTO 488

    Catalog No. SPR-518-A488

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    Expression System E. coli
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    SPR-518-A488_Alpha-Synuclein-E114C-Mutant-Pre-formed-Fibrils-ATTO-488-Protein-ICC-IF-neuronal-uptake-1.png
    Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Representative TEM image of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)Fluorescent signal of alpha-synuclein E114C-ATTO-488 PFFs (SPR-518-A88)In vitro seeding activity of human Alpha Synuclein wildtype monomer in ThT assay. (SPR-518-A88)Sedimentation assay on ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils. (SPR-518-A88)SDS-PAGE analysis of ATTO-488 conjugated Alpha Synuclein E114C Pre-Formed Fibrils (SPR-518-A88)

  • Alpha Synuclein Filaments

    Human Recombinant Alpha Synuclein Filaments

    Catalog No. SPR-450

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    Expression System E. coli
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    SKU: SPR-450 Category:

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    SPR-450_Alpha-Synuclein-Protein-Filaments-Protein-TEM-2.png
    TEM of Active Human Recombinant Alpha Synuclein Protein Filaments (SPR-450)

  • Alpha Synuclein Monomers

    Mouse Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein Monomers

    Rat Recombinant Alpha Synuclein Monomers

    Catalog No. SPR-481

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    Expression System E. coli
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    SPR-481_Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T Fluorescence Activity for Rat Alpha Synuclein Protein (SPR-481)