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| Product Name | Flupirtine maleate |
| Description |
Kv7 channel activator |
| Purity | >98% (HPLC) |
| CAS No. | 75507-68-5 |
| Molecular Formula | C15H17FN4O2•C4H4O4 |
| Molecular Weight | 420.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Activator |
| Solubility | Soluble in DMSO (100 mM) and ethanol (10 mM) |
| Source | Synthetic |
| Appearance | White solid |
| SMILES | CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=CC(=O)O)C(=O)O |
| InChI | InChI=1S/C15H17FN4O2.C4H4O4/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10;5-3(6)1-2-4(7)8/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20);1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChIKey | DPYIXBFZUMCMJM-BTJKTKAUSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | Flupirtine maleate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-376) |
Biological Description
| Alternative Names | N-[2-Amino-6-[[4-fluorophenyl)methy-l]amino]-3-pyridinyl]carbamic acid ethyl ester maleate |
| Research Areas | Ion Channels, Neuroscience, Potassium Channels, Voltage-Gated Potassium Channels |
| PubChem ID | 6435335 |
| Scientific Background | Flupirtine maleate is a triaminopyridine derivative salt. It has non-opioid analgesic, neuroprotection, antiapoptic and muscle relaxation properties. Oral Flupirtine provides the same analgesic pain relief administered to individuals without the side effects of non-steroidal anti-inflammatory drugs (1-2). |
| References |
1. Naser SM., Sarkar N., Biswas A., Kamal F., Prakash R., Rahaman QM., Das AK. (2012) J Indian med Assoc. 110(3): 158-60. 2. Harish S., Bhuvana K., Bengalorkar G. and Kumar TN. (2012) J Anaethesiol Clin Pharmacol. 28(2): 172-177. |
Product Images
Chemical structure of Flupirtine maleate (SIH-376), a Kv7 channel activator. CAS #: 75507-68-5. Molecular Formula: C15H17FN4O2.C4H4O4. Molecular Weight: 420.4 g/mol.
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