Custom Modification of Existing Catalog Product Contact InformationName(Required) First Last Institution/Company(Required) Email(Required) Enter Email Confirm Email Phone#(Required)Address(Required) Street Address City State / Province / Region ZIP / Postal Code Country AfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCabo VerdeCambodiaCameroonCanadaCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos IslandsColombiaComorosCongoCongo, Democratic Republic of theCook IslandsCosta RicaCroatiaCubaCuraçaoCyprusCzechiaCôte d'IvoireDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEswatiniEthiopiaFalkland IslandsFaroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and McDonald IslandsHoly SeeHondurasHong KongHungaryIcelandIndiaIndonesiaIranIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People's Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People's Democratic RepublicLatviaLebanonLesothoLiberiaLibyaLiechtensteinLithuaniaLuxembourgMacaoMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesiaMoldovaMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorth MacedoniaNorthern Mariana IslandsNorwayOmanPakistanPalauPalestine, State ofPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarRomaniaRussian FederationRwandaRéunionSaint BarthélemySaint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint MartinSaint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint MaartenSlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwedenSwitzerlandSyria Arab RepublicTaiwanTajikistanTanzania, the United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkmenistanTurks and Caicos IslandsTuvaluTürkiyeUS Minor Outlying IslandsUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuelaViet NamVirgin Islands, BritishVirgin Islands, U.S.Wallis and FutunaWestern SaharaYemenZambiaZimbabweÅland Islands Product DetailsProtein of Interest(Required) Alpha Synuclein Tau Amyloid Beta Other Alpha Synuclein Proteins Available for Custom Modification:If the Alpha Synuclein protein of interest isn't listed below, please choose the "Custom-Made Protein" form on the previous page.Please choose oneSPR-321, Alpha Synuclein Monomers (Type 1)SPR-322, Alpha Synuclein Pre-formed Fibrils (Type 1)SPR-323, Alpha Synuclein Monomers (Type 1)SPR-324, Alpha Synuclein Pre-formed Fibrils (Type 1)SPR-325, Alpha Synuclein A53T Mutant Monomers (Type 1)SPR-326, Alpha Synuclein A53T Mutant Pre-formed Fibrils (Type 1)SPR-331, Alpha Synuclein N-Terminal Acetylated Monomers (Type 1)SPR-332, Alpha Synuclein N-Terminal Acetylated Pre-formed Fibrils (Type 1)SPR-450, Alpha Synuclein FilamentsSPR-481, Alpha Synuclein MonomersSPR-482, Alpha Synuclein Pre-formed FibrilsSPR-499, Alpha Synuclein S87N Mutant MonomersSPR-500, Alpha Synuclein S87N Mutant Pre-formed FibrilsSPR-503, Alpha Synuclein TNG (A53T, S87N, N103G) Mutant MonomersSPR-504, Alpha Synuclein TNG (A53T, S87N, N103G) Mutant Pre-formed FibrilsSPR-505, Alpha Synuclein S129A Mutant MonomersSPR-506, Alpha Synuclein S129A Mutant Pre-formed FibrilsSPR-478, Alpha Synuclein A90C Mutant MonomersSPR-517-A488, Alpha Synuclein E114C Mutant Monomers: ATTO 488SPR-518-A488, Alpha Synuclein E114C Mutant Pre-formed Fibrils: ATTO 488Tau Proteins Available for Custom Modification:If the Tau protein of interest isn't listed below, please choose the "Custom-Made Protein" form on the previous page.Please choose oneSPR-327, Tau-441 (2N4R) P301S Mutant MonomersSPR-328, Tau (K18) P301L Mutant MonomersSPR-329, Tau-441 (2N4R) P301S Mutant Pre-formed FibrilsSPR-330, Tau (K18) P301L Mutant Pre-formed FibrilsSPR-444, Tau Truncated Fragment (AA297-391) (dGAE) MonomersSPR-445, Tau Truncated Fragment (AA297-391) (dGAE C322A) MonomersSPR-461, Tau Truncated Fragment (AA297-391) (dGAE) Pre-formed FibrilsSPR-462, Tau Truncated (AA297-391) (dGAE C322A) Pre-formed FibrilsSPR-463, Tau-441 (2N4R) P301S Mutant FilamentsSPR-471, Tau-441 (2N4R) P301S Mutant Pre-formed FibrilsSPR-473, Tau-441 (2N4R) P301S Mutant MonomersSPR-474, Tau-430 (2N4R) P290S Mutant MonomersSPR-475, Tau-430 (2N4R) P290S Mutant Pre-formed FibrilsSPR-476, Tau (K18) Delta K280 Mutant MonomersSPR-477, Tau (K18) Delta K280 Mutant Pre-formed FibrilsSPR-479, Tau-441 (2N4R) Wild-Type MonomersSPR-480, Tau-441 (2N4R) Wild-Type Pre-formed FibrilsSPR-490, Tau-352 (fetal 0N3R) Wild-Type MonomersSPR-491, Tau-352 (fetal 0N3R) Wild-Type Pre-formed FibrilsSPR-494, Tau-352 (0N3R) and Alpha Synuclein Co-Polymer FibrilsSPR-495, Tau-441 (2N4R) and Alpha Synuclein Co-Polymer FibrilsSPR-496, Tau-441 (2N4R) Wild-Type Monomers (Baculovirus/Sf9)SPR-498, Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9)SPR-501, Tau dGAE (297-391) MonomersSPR-502, Tau dGAE (297-391) AD-mimic Pre-formed FibrilsSPR-509, Tau-383 (0N4R) Wild-Type MonomersSPR-510, Tau-383 (0N4R) Wild-Type Pre-formed FibrilsSPR-511, Tau-412 (1N4R) Wild-Type MonomersSPR-512, Tau-412 (1N4R) Wild-Type Pre-formed FibrilsSPR-513, Tau-381 (1N3R) Wild-Type MonomersSPR-514, Tau-381 (1N3R) Wild-Type Pre-formed FibrilsSPR-515, Tau-441 (2N4R) P301S Mutant Monomers (CHO-expressed, N-glycosylated)SPR-516, Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils (CHO-expressed, N-glycosylated)Amyloid Beta Proteins Available for Custom Modification:If the Amyloid Beta protein of interest isn't listed below, please choose the "Custom-Made Protein" form on the previous page.Please choose oneSPR-485, Amyloid Beta Peptide 1-42 (HFIP treated) MonomersSPR-487, Amyloid Beta 1-42 Pre-formed FibrilsSPR-492, Amyloid Beta Pyroglutamate 3-42 Pre-formed FibrilsOther Proteins Available for Custom Modification:If the "Other" protein of interest isn't listed below, please choose the "Custom-Made Protein" form on the previous page.Please choose oneSPR-405, Beta Synuclein MonomersSPR-457, Beta Synuclein Pre-formed Fibrils (Type 1)SPR-407, Gamma Synuclein MonomersSPR-459, Gamma Synuclein Pre-formed Fibrils (Type 1)SPR-435, Superoxide Dismutase (SOD) MonomersSPR-470, Superoxide Dismutase (SOD) Pre-formed FibrilsSPR-451, Transthyretin L55P Variant MonomersSPR-452, Transthyretin Y78F Variant MonomersSPR-464, Transthyretin L55P Variant FilamentsSPR-465, Transthyretin Y78F Variant FilamentsConstruct(Required) Monomers Fibrils (PFFs) Conjugated Monomers Conjugated Fibrils (PFFs) Other Other Construct Please make sure the protein you selected matches with the Construct. e.g. if you chose "SPR-321, Alpha Synuclein Monomers (Type 1)" then the Construct should be MonomersPlease make sure the protein you selected matches with the Construct. e.g. if you chose "SPR-321, Alpha Synuclein Monomers (Type 1)" then the Construct should be MonomersPlease make sure the protein you selected matches with the Construct. e.g. if you chose "SPR-321, Alpha Synuclein Monomers (Type 1)" then the Construct should be MonomersPlease make sure the protein you selected matches with the Construct. e.g. if you chose "SPR-321, Alpha Synuclein Monomers (Type 1)" then the Construct should be MonomersPlease make sure the protein you selected matches with the Construct. e.g. if you chose "SPR-321, Alpha Synuclein Monomers (Type 1)" then the Construct should be MonomersModifications(Required)Please choose all the modifications that you need for this custom product. Custom Protein Concentration (StressMarq standard is 2mg/mL) Custom Conjugation Custom Buffer Formulation Other Other modification Please select Conjugated Monomers for the Construct of Interest if you want conjugation.Please select Conjugated Fibrils (PFFs) for the Construct of Interest if you want conjugation.Please select Conjugated Monomers and Conjugated Fibrils (PFFs) for the Construct of Interest if you want conjugation.Custom Protein Concentration 2mg/mL (StressMarq standard) 5mg/mL 8mg/mL Other Other Custom Protein Concentration NOTE: SPR-322 @5mg/mL is an existing catalog product; click here to see ordering details!NOTE: SPR-321 @5mg/mL is an existing catalog product; click here to see ordering details!NOTE: SPR-323 @5mg/mL is an existing catalog product; click here to see ordering details!NOTE: SPR-324 @5mg/mL is an existing catalog product; click here to see ordering details!Custom ConjugationPlease choose oneATTO 390ATTO 488ATTO 594Alkaline PhosphataseAPCBiotinFITCHRPPerCPRPEOtherNOTE: SPR-322-A594 is an existing catalog product; click here to see ordering details!NOTE: SPR-329-A488 is an existing catalog product; click here to see ordering details!Other Conjugation: Preferred Conjugation Method(Required) NHS ester Maleimide-based No preference Custom Buffer Formulation(Required) PBS, pH 7.4 (StressMarq standard) Other Other Custom Buffer Formulation Custom Buffer Composition - Azide(Required) With Azide Without Azide Other Other Custom Buffer Composition - Azide Buffer Composition - Reducing Agent(Required) No Reducing Agent Required TCEP BME DTT Other Other Buffer Composition - Reducing Agent Required Amount (NOTE: Minimum is 1mg)(Required) 1mg 2mg 5mg Other (minimum is 1 mg) Other Required Amount Preferred Aliquot Size(Required) 50uL 100uL No preference Other Other Preferred Aliquot Size Customer Required Quality Control – Modification of Existing ProductPlease choose the Quality Control (QC) testing you require for this product. Quality Control (QC) Testing for MONOMERS SDS-PAGE & Nanodrop A280 Endotoxin ≤ 5 EU/mL @ 2mg/mL (StressMarq standard) Sterility Activity assay, if applicable Other Quality Control Testing** ** NOTE: Additional charge and extended lead time may apply for options with asterisks**Other Quality Control Testing for MONOMERS** Quality Control (QC) Testing for FIBRILS (PFFs) SDS-PAGE & Nanodrop A280 Endotoxin ≤ 5 EU/mL @ 2mg/mL (StressMarq standard) Sterility Sedimentation Assay Seeding Assay Atomic Force Microscopy (AFM) Other Quality Control Testing** ** NOTE: Additional charge and extended lead time may apply for options with asterisks**Other Quality Control Testing for FIBRILS (PFFs)** Quality Control (QC) Testing for CONJUGATED MONOMERS Pre-conjugation SDS-PAGE & Nanodrop A280 Pre-conjugation Endotoxin ≤ 5 EU/mL @ 2mg/mL Pre-conjugation Sterility Pre-conjugation Activity Assay Post-conjugation SDS-PAGE & Nanodrop A280 Post-conjugation signal/monomer concentration curve Post-conjugation Sterility Post-conjugation Endotoxin ≤ 5 EU/mL @ 2mg/mL** Post-conjugation Aggregation Competent** Other Quality Control Testing**: ** NOTE: Additional charge and extended lead time may apply for options with asterisks** Other Quality Control Testing for CONJUGATED MONOMERS** Quality Control (QC) Testing for CONJUGATED FIBRILS (PFFs) Pre-conjugation SDS-PAGE & Nanodrop A280 Pre-conjugation Endotoxin ≤ 5 EU/mL @ 2mg/mL Pre-conjugation Sterility Pre-conjugation Sedimentation Assay Pre-conjugation Seeding Assay Pre-conjugation Atomic Force Microscopy (AFM) Post-conjugation SDS-PAGE & Nanodrop A280 Post-conjugation signal/fibril concentration curve Post-conjugation Sterility** Post-conjugation Endotoxin ≤ 5 EU/mL @ 2mg/mL** Post-conjugation Seeding Competent** Other Quality Control Testing** ** NOTE: Additional charge and extended lead time may apply for options with asterisks** Other Quality Control Testing for CONJUGATED FIBRILS (PFFs)** Δ
