Z-Guggulsterone

FXR Antagonist

Catalog No. SIH-591

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CAS No. 39025-23-5
Molecular Formula C21H28O2
SKU: SIH-591 Categories: ,

SIH-591-Z-Guggulsterone-Chemical-Structure.png
Product Name Z-Guggulsterone
Description

FXR Antagonist

Purity >98% (TLC); NMR (Conforms)
CAS No. 39025-23-5
Molecular Formula C21H28O2
Molecular Weight 312.5
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antagonist
Solubility May be dissolved in DMSO (6 mg/ml, warm); or Ethanol (3 mg/ml, warm)
Source Synthetic
Appearance Off-white powder
SMILES CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
InChI InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
InChIKey WDXRGPWQVHZTQJ-OSJVMJFVSA-N
Safety Phrases Classification:
Not a hazardous substance or mixture.

Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product Z-Guggulsterone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-591)

Biological Description

Alternative Names (Z)-Pregna-4,17(20)-diene-3,16-dione
Research Areas Apoptosis, Cancer
PubChem ID 6450278
Scientific Background Z-Guggulsterine acts as a selective antagonist at farnesoid X receptors, and inhibits FXR transactivation. It is also a retinoic acid receptor (RAR) pathway inhibitor.

Product Images

<p>Chemical structure of Z-Guggulsterone (SIH-591), a FXR Antagonist. CAS #: 39025-23-5. Molecular Formula: C21H28O2. Molecular Weight: 312.5 g/mol.</p>

Chemical structure of Z-Guggulsterone (SIH-591), a FXR Antagonist. CAS #: 39025-23-5. Molecular Formula: C21H28O2. Molecular Weight: 312.5 g/mol.

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