Products

  • Alpha Synuclein Pre-formed Fibrils: ATTO 594

    Human Recombinant Alpha Synuclein PFFs: ATTO 594 (Type 1)

    Catalog No. SPR-322-A594

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    Expression System E. coli
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    SPR-322-A594_Alpha-Synuclein-Protein-Protein-TEM-1.png
    Thioflavin T Assay for SPR-322-A594Human iPSC-derived neurons seeded with ATTO594 labelled alpha synuclein PFFs (SPR-322-A594)TEM of ATTO conjugated alpha syuclein pre-formed fibrils

  • Alpha Synuclein Monomers

    Mouse Recombinant Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein A53T Mutant Monomers

    Human Recombinant Alpha Synuclein A53T Mutant Monomers (Type 1)

    Catalog No. SPR-325

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    Expression System E. coli
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    SPR-325_A53T-Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.Cisbio Total Alpha Synuclein AssayCisbio Alpha Synuclein Aggregation Assay

  • Alpha Synuclein A53T Mutant Pre-formed Fibrils

    Human Recombinant Alpha Synuclein A53T Mutant PFFs (Type 1)

    Catalog No. SPR-326

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    Expression System E. coli
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    SPR-326_A53T-Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-2.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.ICC/IF of human A53T Alpha Synuclein Preformed Fibrils Protein (SPR-326)ICC/IF of human A53T Alpha Synuclein Preformed Fibrils Protein (SPR-326)ICC of primary rat neurons treated with A53T alpha synuclein PFFs show Lewy body inclusion formation.Cisbio Alpha Synuclein Aggregation AssayCisbio Total Alpha Synuclein AssayLDH assay shows effect of A53T alpha synuclein PFFs on mouse primary neuronsMTT assay effects of A53T alpha synuclein PFFs on mouse primary neuronsTEM of A53T alpha synuclein pre-formed fibrils (SPR-326).

  • Tau (K18) P301L Mutant Monomers

    Human Recombinant Tau (K18) P301L Mutant Monomers

    Catalog No. SPR-328

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    Expression System E. coli
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    SPR-328_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) in tau K18 P301L monomers (SPR-328) over time.

  • Tau (K18) P301L Mutant Pre-formed Fibrils

    Human Recombinant Tau (K18) P301L Mutant PFFs

    Catalog No. SPR-330

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    Expression System E. coli
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    SPR-330_Tau-Preformed-Fibrils-Protein-IHC-1.png
    Comparison of AT8 (pSer202/pThr205) tau inclusions in P301L mice injected with K18 PFFs and negative control.TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau Pre-formed fibrils (SPR-330). Tau Pre-formed fibrils (SPR-330) seed the formation of new tau fibrils when combined with tau monomers (SPR-327)SDS-PAGE of ~15 kDa Human Tau Protein K18/P301L Pre-formed Fibrils (SPR-330)

  • Beta Synuclein Monomers

    Human Recombinant Beta Synuclein Monomers

    Catalog No. SPR-405

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    Expression System E. coli
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    SPR-405_Beta-Synuclein-Protein-Protein-Thioflavin-T-assay-1.png
    Coomassie gel stain of beta synuclein monomer (SPR-405)

  • Gamma Synuclein Monomers

    Human Recombinant Gamma Synuclein Monomers

    Catalog No. SPR-407

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    Expression System E. coli
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    SPR-407_Gamma-Synuclein-Monomer-Protein-Thioflavin-T-assay-1.png
    Coomassie gel stain of gamma synuclein monomer (SPR-407)

  • SOD1 Monomers

    Human Recombinant Superoxide Dismutase 1 (SOD1) Monomers

    Catalog No. SPR-435

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    Expression System E. coli
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    SPR-435_SOD1-Protein-SDS-PAGE-1.png
    Thioflavin T assay of SOD1 fibrils and monomers

  • Tau dGAE (297-391) Monomers

    Human Recombinant Tau dGAE (297-391) Monomers

    Catalog No. SPR-444

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    Expression System E. coli
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    SPR-444_Tau-Protein-Monomer-Protein-Thioflavin-T-assay-1.png
    Coomassie gel stain of Human dGAE Tau protein monomer (SPR-444)