Alzheimer's Disease

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  • Tau-441 (2N4R) P301S Mutant Monomers

    Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers (CHO-expressed, N-glycosylated)

    Catalog No. SPR-515

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    Expression System Chinese Hamster Ovary (CHO)
    Tags N-term histidine tag & TEV site
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    SPR-515_Tau-441-2N4R-P301S-Mutant-Monomers-CHO-expressed-N-glycosylated-Protein-SDS-Page-1.png
    SDS-PAGE of SPR-515 glycosylation.Mass spectrometry of human P301S Tau 2N4R monomers expressed using CHO cells (SPR-515).Mass spectrometry of human P301S Tau 2N4R monomers expressed using CHO cells (SPR-515).Dot Blot of purified hTau (2N4R) P301S monomers (SPR-515)

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs

    Catalog No. SPR-329

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    Expression System E. coli
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    SKU: SPR-329 Category:

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    SPR-329_Tau-Protein-Peformed-Fibrils-TEM-1.png
    TEM of recombinant Tau441 (2N4R), P301S mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) when tau Pre-formed fibrils (SPR-329) are combined with tau monomers (SPR-327). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.SDS-PAGE of ~67 kDa Human Tau 2N4R P301S Pre-formed Fibrils (PFFs)

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs (Baculovirus/Sf9)

    Catalog No. SPR-471

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    Expression System Baculovirus (Sf9)
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    SPR-471_Tau-Protein-TEM-1.png
    Thioflavin T assay of tau pre-formed fibrils (SPR-471)Mass spectrometry analysis of tau PFFs (SPR-471)

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs (CHO-expressed, N-glycosylated)

    Catalog No. SPR-516

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    Expression System Chinese Hamster Ovary (CHO)
    Tags N-term histidine tag & TEV site
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    SPR-516_Tau-441-2N4R-P301S-Mutant-Pre-formed-Fibrils-CHO-expressed-N-glycosylated-Protein-TEM-1.png
    Native-PAGE of CHO-expressed Tau monomers (SPR-515) & fibrils (SPR-516)ThT fluorescence (excitation at 450nm, emission at 485nm) of CHO-expressed Tau monomers (SPR-515) and pre-formed fibrils (SPR-516)SDS-PAGE of SPR-516 glycosylation.Mass spectrometry of human P301S Tau 2N4R monomers expressed using CHO cells (SPR-515).Mass spectrometry of human P301S Tau 2N4R monomers expressed using CHO cells (SPR-515).Dot Blot of purified hTau (2N4R) P301S monomersRepresentative TEM image of Cho-expressed Tau 2N4R P301S Pre-Formed Fibrils (SPR-516)Atomic force microscopy analysis of Cho-expressed Tau 2N4R P301S Pre-Formed Fibrils (SPR-516)

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs: ATTO 488

    Catalog No. SPR-329-A488

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    Expression System E. coli
    Tags ATTO 488
    SKU: SPR-329-A488 Category:

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    SPR-329-A488_Tau-Protein-Protein-TEM-1.png
    TEM of ATTO conjugated tau pre-formed fibrilsThioflavin T assay of ATTO-488 conjugated tau fibrils

  • Tau-441 (2N4R) Wild-Type Monomers

    Human Recombinant Tau-441 (2N4R) Wild-Type Monomers

    Catalog No. SPR-479

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    Expression System E. coli
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    SPR-479_Tau-Protein-SDS-PAGE-1.png
    Thioflavin T assay of Tau Wild-Type fibrils (SPR-480) and monomers (SPR-479)

  • Tau-441 (2N4R) Wild-Type Monomers

    Human Recombinant Tau-441 (2N4R) Wild-Type Monomers (Baculovirus/Sf9)

    Catalog No. SPR-496

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    Expression System Baculovirus (Sf9)
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    SPR-496_Tau-441-2N4R-Wild-Type-Monomers-Baculovirus-Sf9-Protein-SDS-PAGE-1
    Dot Blot of Human Tau-441 (2N4R) Wild-Type Monomers (Baculovirus/Sf9) Protein (SPR-496)Mass Spec Table of Human Tau-441 (2N4R) Wild-Type Monomers (Baculovirus/Sf9) Protein (SPR-496)

  • Tau-441 (2N4R) Wild-Type Oligomers

    Human Recombinant Tau-441 (2N4R) Wild-Type Oligomers (Baculovirus/Sf9)

    Catalog No. SPR-497

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    Expression System Baculovirus (Sf9)
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    SPR-497_Tau-441-2N4R-Wild-Type-Oligomers-Protein-AFM-1.png
    Native-PAGE of Tau-441 (2N4R) Wild-Type Oligomers (SPR-497)Toxicity of Tau-441 (2N4R) Wild-Type Oligomers (SPR-497)SDS-Page of Tau-441 (2N4R) Wild-Type Oligomers (SPR-497)Dot Blot of Tau-441 (2N4R) Wild-Type Oligomers (SPR-497)

  • Tau-441 (2N4R) Wild-Type Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) Wild-Type PFFs

    Catalog No. SPR-480

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    Expression System E. coli
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    SPR-480_Tau-Protein-TEM-1.png
    TEM of human recombinant tau wild-type PFFs (SPR-480)Thioflavin T assay of Tau Wild-Type fibrils (SPR-480) and monomers (SPR-479)

  • Tau-441 (2N4R) Wild-Type Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) Wild-Type PFFs (Baculovirus/Sf9)

    Catalog No. SPR-498

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    Expression System Baculovirus (Sf9)
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    SPR-498_Tau-441-2N4R-Wild-Type-Pre-formed-Fibrils-Baculovirus-Sf9-Protein-TEM-1.png
    SDS-PAGE of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)Mass Spec Table of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)AFM of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)TEM of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)TEM of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)TEM of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)Toxicity of Human Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (Baculovirus/Sf9) Protein (SPR-498)

  • Transthyretin (TTR) L55P Variant Filaments

    Human Recombinant Transthyretin (TTR) L55P Variant Filaments

    Catalog No. SPR-464

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    Expression System E. coli
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    SPR-464_TTR-Protein-Filaments-Protein-TEM-1.png
    Turbidity Assay shows increased turbidity in Human Recombinant Transthyretin L55P Variant Protein Filaments (SPR-464)

  • Transthyretin (TTR) L55P Variant Monomers

    Human Recombinant Transthyretin (TTR) L55P Variant Monomers

    Catalog No. SPR-451

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    Expression System E. coli
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    SPR-451_Transthyretin-Protein-SDS-PAGE-1.png

  • Transthyretin (TTR) Y78F Variant Filaments

    Human Recombinant Transthyretin (TTR) Y78F Variant Filaments

    Catalog No. SPR-465

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    Expression System E. coli
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    SPR-465_TTR-Protein-Filaments-Protein-Turbidity-Assay-1.png

  • Transthyretin (TTR) Y78F Variant Monomers

    Human Recombinant Transthyretin (TTR) Y78F Variant Monomers

    Catalog No. SPR-452

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    Expression System E. coli
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    SPR-452_Transthyretin-Protein-SDS-PAGE-1.png

  • Anti-TRPM7 Antibody [S74]

    Mouse Anti-Mouse TRPM7 Monoclonal IgG1

    Catalog No. SMC-316

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    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-316 Categories: ,

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    SMC-316_TrpM7_Antibody_S74_ICC-IF_Human_Neuroblastoma-cells-SH-SY5Y-Composite-1.png
    Mouse Anti-TrpM7 Antibody [S74] used in Immunohistochemistry (IHC) on Mouse Brain Slice (SMC-316)Mouse Anti-TrpM7 Antibody [S74] used in Immunohistochemistry (IHC) on Human hippocampus (SMC-316)Mouse Anti-TrpM7 Antibody [S74] used in Western Blot (WB) on Human cell line mix (A431, A549, HCT116, HeLa, HEK293, HepG2, HL-60, HUVEC, Jurkat, MCF7, PC3, T98G) (SMC-316)

  • Anti-Ubiquitin Antibody

    Rabbit Anti-Bovine Ubiquitin Polyclonal

    Catalog No. SPC-119

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    Species Reactivity Hu, Ms, Rt, Bv, Mk, Hm, Rb, GP, Pg, Dg, Sh, Ck, Xe, Ys, Dr, Fs, ,
    Applications WB IHC ICC/IF FCM IP
    SKU: SPC-119 Categories: ,

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    SPC-119_Ubiquitin_Antibody_ICC-IF_Human_Heat-Shocked-HeLa-Cells_100x_Composite.png
    Rabbit Anti-Ubiquitin Antibody used in Western blot (WB) on Human Embryonic kidney epithelial cell line (HEK293) lysate (SPC-119)Rabbit Anti-Ubiquitin Antibody used in Immunohistochemistry (IHC) on Mouse backskin (SPC-119)Rabbit Anti-Ubiquitin Antibody used in Immunohistochemistry (IHC) on Human colon carcinoma (SPC-119)Rabbit Anti-Ubiquitin Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Cervical cancer cell line (HeLa) (SPC-119)