Parkinson's Disease

Showing 1–0 of 71 results

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2)

    Catalog No. SPR-317

    3.3333333333333 out of 5 based on 3 customer ratings
    Reviews (3)
    Expression System E. coli
    Tags No tag
    SKU: SPR-317 Category:

    Clear
    + Compare Bulk Quote
    SPR-317_Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-4.png
    TEM of Type 2 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-317)Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.SDS-Page of Type 2 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-317)Type 2 alpha synuclein Pre-formed fibrils (SPR-317) do not seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) at the same rate as Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by lower fluorescence intensity values of Thioflavin T over time.Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)LDH assay shows effect of alpha synuclein PFFs on mouse primary neuronsMTT assay effects of alpha synuclein PFFs on mouse primary neurons

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Monomers (Type 1)

    Catalog No. SPR-321

    5 out of 5 based on 1 customer rating
    Reviews (1)
    Expression System E. coli
    Tags No tag
    SKU: SPR-321 Category:

    Clear
    + Compare Bulk Quote
    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-322

    5 out of 5 based on 1 customer rating
    Reviews (1)
    Expression System E. coli
    Tags No tag
    SKU: SPR-322 Category:

    Clear
    + Compare Bulk Quote
    SPR-322_Alpha-Synuclein-Protein-Preformed-Fibrils-Protein-TEM-7.png
    Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.StressMarq’s Alpha Synuclein PFFs (red) cat#SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days.SDS-Page of Type 1 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-322)Type 1 alpha synuclein Pre-formed Fibrils (SPR-322) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) as shown by increased fluorescence intensity by Thioflavin T over time.Immunocytochemistry/Immunofluorescence of Human Alpha Synuclein Protein Protein (SPR-322)Mouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFsMouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFs cause endogenous alpha synuclein phosphorylationTEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-322)IHC of Sprague-Dawley rat brain injected with Type 1 human alpha synuclein Pre-formed Fibrils (SPR-322)Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Monomers (Type 2)

    Catalog No. SPR-316

    0 out of 5 based on 0 customer ratings
    Reviews (0)
    Expression System E. coli
    Tags No tag
    SKU: SPR-316 Category:

    Clear
    + Compare Bulk Quote
    SPR-316_Alpha-Synuclein-Protein-Monomer-Protein-SDS-Page-1.png
    Alpha Synuclein monomers (SPR-316) do not form new alpha synuclein fibrils when combined with Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by a limited increase in fluorescence intensity by Thioflavin T over time.Alpha Synuclein Monomer RT-QuiC AssayΑlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.LDH assay shows effect of alpha synuclein monomers on mouse primary neuronsMTT assay shows effects of alpha synuclein monomers on mouse primary neurons

  • Fasudil

    ROCK inhibitor

    Catalog No. SIH-371

    0 out of 5 based on 0 customer ratings
    Reviews (0)
    CAS No. 103745-39-7
    Molecular Formula C14H17N3O2S•HCl
    SKU: SIH-371 Categories: ,

    Clear
    + Compare Bulk Quote
    SIH-371_Fasudil_Chemical_Structure.png

  • MOLECULAR SIGNATURE® Nitrotyrosine ELISA Kit

    Colorimetric detection of Nitrotyrosine

    Catalog No. SKT-126

    5 out of 5 based on 1 customer rating
    Reviews (1)
    Species Reactivity ALL
    Sample Types Cell lysates, Plasma, Serum, Urine
    SKU: SKT-126 Categories: ,

    Clear
    + Compare Bulk Quote
    SKT-126_Nitrotyrosine_ELISA_Kit_Standard_Curve.png
    Diagram of the Competitive ELISA for the Nitrotyrosine ELISA Kit StressXpress - SKT-126Diagram of the Preparation of Nitrotyrosine Standards for the Nitrotyrosine ELISA Kit StressXpress - SKT-126Diagram of the Triplicate Sample Plate Format for the Nitrotyrosine ELISA Kit StressXpress - SKT-126

  • Tolcapone

    COMT inhibitor

    Catalog No. SIH-540

    0 out of 5 based on 0 customer ratings
    Reviews (0)
    CAS No. 134308-13-7
    Molecular Formula C14H11NO5
    SKU: SIH-540 Categories: ,

    Clear
    + Compare Bulk Quote
    SIH-540-Tolcapone-Chemical-Structure.png