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Heat Shock Protein Antibodies
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Heat Shock Protein Proteins
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Target Focus: Hsp70 Product Suite
Heat Shock Proteins (HSPs) were initially discovered as proteins that were markedly induced by heat shock and other chemical or physical stresses. Since that time they have viewed as molecular chaperones, guiding and modifying the structures of proteins by their intrinsic ability to re-fold them from a denatured to a native structure. These interactions and the balance toward fully-natured functional proteins necessitates that the HSPs be abundant. more... |
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Target Focus: Hsp90 Product Suite
Hsp90 is one of a number of classes of heat shock proteins (Hsps), which are generally synthesized in response to cellular stress as well as being constitutively expressed in some cases. These types of stress are numerous, but include heat shock, metal toxicity, nutrient deprivation, oxidative stress as well as numerous disease states of which cancer has received the most attention. Hsps function is several ways, but have the ability to form complexes with client proteins and act as molecular chaperones. more... |
